ArticleNature communications2016
Re-entrant DNA gels.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Designing DNA nanostar hydrogels for sequence-specific degradation and antibody release.Soft matter · 2026Article
- Organization and Triggered Release of Liposomes with DNA-Based Synthetic Condensates.ACS nano · 2026Article
- Phase-transition-like behaviors of sequence-selective dynamic bonds.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections.Nature biomedical engineering · 2025Article
- Mechanically Tunable DNA Hydrogels as Prospective Biosensing Modules.Macromolecular rapid communications · 2025Article
- Inverse Thermodynamics: Designing Interactions for Targeted Phase Behavior.The journal of physical chemistry. B · 2025Article
- Remote-controlled mechanical and directional motions of photoswitchable DNA condensates.Nature communications · 2025Article
- DNA-empowered synthetic cells as minimalistic life forms.Nature reviews. Chemistry · 2024Review
- Review
- Dynamic control of DNA condensation.Nature communications · 2024Article
- Interpenetrated and Bridged Nanocylinders from Self-Assembled Star Block Copolymers.Macromolecules · 2024Article
- Entropy-Driven Thermo-gelling Vitrimer.JACS Au · 2022Article
- Formation of non-base-pairing DNA microgels using directed phase transition of amphiphilic monomers.Nucleic acids research · 2022Article
- Rational design of hydrogels to enhance osteogenic potential.Chemistry of materials : a publication of the American Chemical Society · 2020Article
- Chirality dependent inverse-melting and re-entrant gelation in α-cyclodextrin/1-phenylethylamine mixtures.RSC advances · 2020Article
- Gelling without Structuring: A SAXS Study of the Interactions among DNA Nanostars.Langmuir : the ACS journal of surfaces and colloids · 2020Article
- Sequence-based engineering of dynamic functions of micrometer-sized DNA droplets.Science advances · 2020Article
- DNA-GEL, Novel Nanomaterial for Biomedical Applications and Delivery of Bioactive Molecules.Frontiers in pharmacology · 2020Review
- Thermal cycling of DNA devices via associative strand displacement.Nucleic acids research · 2019Article
- Application of DNA Quadruplex Hydrogels Prepared from Polyethylene Glycol-Oligodeoxynucleotide Conjugates to Cell Culture Media.Polymers · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA is acquiring a primary role in material development, self-assembling by design into complex supramolecular aggregates, the building block of a new-materials world. Using DNA nanoconstructs to translate sophisticated theoretical intuitions into experimental realizations by closely matching idealized models of colloidal particles is a much less explored avenue. Here we experimentally show that an appropriate selection of competing interactions enciphered in multiple DNA sequences results into the successful design of a one-pot DNA hydrogel that melts both on heating and on cooling. The relaxation time, measured by light scattering, slows down dramatically in a limited window of temperatures. The phase diagram displays a peculiar re-entrant shape, the hallmark of the competition between different bonding patterns. Our study shows that it is possible to rationally design biocompatible bulk materials with unconventional phase diagrams and tuneable properties by encoding into DNA sequences both the particle shape and the physics of the collective response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.