Evidence map›Paper›PMID 27766895›Full record

ReviewJournal of enzyme inhibition and medicinal chemistry2017

Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage.

Daria M Monti, Giuseppina De Simone, Emma Langella, Claudiu T Supuran, Anna Di Fiore, Simona M Monti

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of enzyme inhibition and medicinal chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Carbonic Anhydrase Inhibitors in Oncology.Sub-cellular biochemistry · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. α-CAs from Photosynthetic Organisms.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Pepsin and Laryngeal and Hypopharyngeal Carcinomas.Clinical and experimental otorhinolaryngology · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Daria M Montia Department of Chemical Sciences , University of Naples Federico II , Naples , Italy.
Giuseppina De Simoneb Institute of Biostructures and Bioimaging, CNR , Naples , Italy.
Emma Langellab Institute of Biostructures and Bioimaging, CNR , Naples , Italy.
Claudiu T Supuranc Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche , Università degli Studi di Firenze , Florence , Italy.
Anna Di Fioreb Institute of Biostructures and Bioimaging, CNR , Naples , Italy.
Simona M Montib Institute of Biostructures and Bioimaging, CNR , Naples , Italy.
Institute of Biostructure and Bioimaging · ITUniversity of Florence · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbonic anhydrases (CAs) III and VII are two cytosolic isoforms of the α-CA family which catalyze the physiological reaction of carbon dioxide hydration to bicarbonate and proton. Despite these two enzymes share a 49% sequence identity and present a very similar three-dimensional structure, they show profound differences when comparing the specific activity for CO

Indexed as

Oxidative StressAmino Acid SequenceCarbonic AnhydrasesCrystallography, X-RaySequence Homology, Amino AcidSulfhydryl CompoundsCarbonic AnhydrasesSulfhydryl CompoundsCarbonic anhydrase IIIcarbonic anhydrase VIIoxidative stressreactive cysteinesS-glutathiolationsulfhydryl groups

Identifiers

PMID27766895
PMCPMC6010095
OpenAlexW2536916777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.