Evidence map›Paper›PMID 27766650›Full record

ArticleAggressive behavior2017

Neural correlates of proactive and reactive aggression in adolescent twins.

Yaling Yang, Shantanu H Joshi, Neda Jahanshad, Paul M Thompson, Laura A Baker

Open access · greenAbstract readTwin Study
In one paragraph

Article in Aggressive behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
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  12. Association between lower-level of environmental lead exposure and reactive and proactive aggression in youth: Sex differences.Journal of environmental science and health. Part C, Toxicology and carcinogenesis · 2022
    Article
  13. Review
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  15. Review
  16. Mobile Phone Addiction and Risk-Taking Behavior among Chinese Adolescents: A Moderated Mediation Model.International journal of environmental research and public health · 2020
    Article
  17. Variants of the Aggression-RelatedFrontiers in psychiatry · 2020
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yaling YangDepartment of Pediatrics, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California.
Shantanu H JoshiDepartment of Neurology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California.
Neda JahanshadDepartment of Neurology, University of Southern California, Los Angeles, California.
Paul M ThompsonDepartment of Neurology, University of Southern California, Los Angeles, California.
Laura A BakerDepartment of Psychology, University of Southern California, Los Angeles, California.
University of Southern California · USUniversity of California, Los Angeles · US

Funding

YALE CENTER FOR THE: LEARNING &ATTENTIONP41RR013642 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SMALL, GARY WILLIAM · 1998 to 2011
$21.9M
RISK FACTORS FOR ANTISOCIAL BEHAVIORR01MH058354 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BAKER, LAURA A · 2000 to 2013
$8.5M
Alzheimer's disease risk analyzed using population imaging genomicsR01AG040060 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2011 to 2016
$2.5M
Brain Structural Variations as Potential Endophenotypes for Psychopathic TraitsR00MH093388 · NIMH · CHILDREN'S HOSPITAL OF LOS ANGELES · PI YANG, YALING · 2013 to 2015
$722k
Brain Structural Variations as Potential Endophenotypes for Psychopathic TraitsK99MH093388 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YANG, YALING · 2011 to 2012
$176k
NCRR NIH HHS P41 RR013642NIA NIH HHS R01 AG040060NIMH NIH HHS K99 MH093388NIMH NIH HHS R00 MH093388NIMH NIH HHS R01 MH058354
6 · The paper itself

Abstract

Verbal and physical aggression begin early in life and steadily decline thereafter in normal development. As a result, elevated aggressive behavior in adolescence may signal atypical development and greater vulnerability for negative mental and health outcomes. Converging evidence suggests that brain disturbances in regions involved in impulse control, emotional regulation, and sensation seeking may contribute to heightened aggression. However, little is known regarding the neural mechanisms underlying subtypes of aggression (i.e., proactive and reactive aggression) and whether they differ between males and females. Using a sample of 106 14-year-old adolescent twins, this study found that striatal enlargement was associated with both proactive and reactive aggression. We also found that volumetric alterations in several frontal regions including smaller middle frontal and larger orbitofrontal cortex were correlated with higher levels of aggression in adolescent twins. In addition, cortical thickness analysis showed that thickness alterations in many overlapping regions including middle frontal, superior frontal, and anterior cingulate cortex and temporal regions were associated with aggression in adolescent twins. Results support the involvement of fronto-limbic-striatal circuit in the etiology of aggression during adolescence. Aggr. Behav. 43:230-240, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

AdolescentAdolescent BehaviorAggressionCerebral CortexFemaleGyrus CinguliHumansMagnetic Resonance ImagingMaleNeostriatumOccipital LobePrefrontal Cortexadolescenceaggressioncortical thicknessfrontal cortexstriatum

Identifiers

PMID27766650
PMCPMC6192547
OpenAlexW2545701559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.