Evidence map›Paper›PMID 27766413›Full record

Trial reportSurgical endoscopy2017

Conversions in laparoscopic surgery for rectal cancer.

Martijn H G M van der Pas, Charlotte L Deijen, Gabor S A Abis, Elly S M de Lange-de Klerk, Eva Haglind, Alois Fürst, Antonio M Lacy, Miguel A Cuesta, Hendrik J Bonjer, COLOR II study group

Open access · greenAbstract readClinical Trial, Phase IIRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Long term oncological outcomes for laparoscopic versus open surgery for rectal cancer - A population-based nationwide noninferiority study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
    Article
  8. Article
  9. High-pressure COUpdates in surgery · 2021
    Article
  10. Article
  11. Transanal total mesorectal excision: how are we doing so far?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2019
    Article
  12. Article
  13. Article
  14. Unplanned Robotic-Assisted Conversion-to-Open Colorectal Surgery is Associated with Adverse Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Martijn H G M van der PasVU University Medical Center, Amsterdam, The Netherlands. martijnvanderpas@gmail.com.ORCID 0000-0002-1577-7264
Charlotte L DeijenVU University Medical Center, Amsterdam, The Netherlands.
Gabor S A AbisVU University Medical Center, Amsterdam, The Netherlands.
Elly S M de Lange-de KlerkVU University Medical Center, Amsterdam, The Netherlands.
Eva HaglindSahlgrenska Universitetssjukhuset Goteborg, Goteborg, Sweden.
Alois FürstCaritas Krankenhaus St Josef Regensburg, Regensburg, Germany.
Antonio M LacyHospital Clinic I Provincial de Barcelona, Barcelona, Spain.
Miguel A CuestaVU University Medical Center, Amsterdam, The Netherlands.
Hendrik J BonjerVU University Medical Center, Amsterdam, The Netherlands.
COLOR II study group
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLHospital Clínic de Barcelona · ESSahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic surgery offers patients with rectal cancer short-term benefits and similar survival rates as open surgery. However, selecting patients who are suitable candidates for laparoscopic surgery is essential to prevent intra-operative conversion from laparoscopic to open surgery. Clinical and pathological variables were studied among patients who had converted laparoscopic surgeries within the COLOR II trial to improve patient selection for laparoscopic rectal cancer surgery.

methodsBetween January 20, 2004, and May 4, 2010, 1044 patients with rectal cancer enrolled in the COLOR II trial and were randomized to either laparoscopic or open surgery. Of 693 patients who had laparoscopic surgery, 114 (16 %) were converted to open surgery. Predictive factors were studied using multivariate analyses, and morbidity and mortality rates were determined.

resultsFactors correlating with conversion were as follows: age above 65 years (OR 1.9; 95 % CI 1.2-3.0: p = 0.003), BMI greater than 25 (OR 2.7; 95 % CI 1.7-4.3: p < 0.001), and tumor location more than 5 cm from the anal verge (OR 0.5; CI 0.3-0.9). Gender was not significantly related to conversion (p = 0.14). In the converted group, blood loss was greater (p < 0.001) and operating time was longer (p = 0.028) compared with the non-converted laparoscopies. Hospital stay did not differ (p = 0.06). Converted procedures were followed by more postoperative complications compared with laparoscopic or open surgery (p = 0.041 and p = 0.042, respectively). Mortality was similar in the laparoscopic and converted groups.

conclusionsAge above 65 years, BMI greater than 25, and tumor location between 5 and 15 cm from the anal verge were risk factors for conversion of laparoscopic to open surgery in patients with rectal cancer.

Indexed as

AgedAge FactorsAnal CanalBlood Loss, SurgicalBody Mass IndexConversion to Open SurgeryFemaleHumansLaparoscopyLength of StayMaleMiddle AgedMultivariate AnalysisOperative TimePatient SelectionPredictive Value of TestsConversionLaparoscopic surgeryRectal cancer

Identifiers

PMID27766413
OpenAlexW2532553928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.