ArticleDiabetes & metabolism journal2016
Effects of Body Weight Reduction on Serum Irisin and Metabolic Parameters in Obese Subjects.
Article in Diabetes & metabolism journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The Effect of Bariatric Surgery on Irisin Level: a Systematic Review and Meta-analysis.Obesity surgery · 2023Pooled it
- Obesity, Osteoarthritis, and Myokines: Balancing Weight Management Strategies, Myokine Regulation, and Muscle Health.Nutrients · 2024Review
- Association between changes in body composition and progression of liver fibrosis in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2024Article
- Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity.Sports medicine - open · 2023Review
- Review
- Article
- An early prediction model for gestational diabetes mellitus based on genetic variants and clinical characteristics in China.Diabetology & metabolic syndrome · 2022Article
- The role of exercise-induced myokines in promoting angiogenesis.Frontiers in physiology · 2022Review
- Article
- Progress and Challenges in the Biology of FNDC5 and Irisin.Endocrine reviews · 2021Review
- Exercise-Induced Circulating Irisin Level Is Correlated with Improved Cardiac Function in Rats.International journal of environmental research and public health · 2020Article
- Effect of HIIT with Tabata Protocol on Serum Irisin, Physical Performance, and Body Composition in Men.International journal of environmental research and public health · 2020Article
- Serum irisin levels in metabolically healthy versus metabolically unhealthy obesity: A case-control study.Medical journal of the Islamic Republic of Iran · 2020Article
- Serum Irisin, Adropin, and Preptin in Obese Patients 6 Months After Bariatric Surgery.Obesity surgery · 2019Observational
- Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan.Journal of epidemiology · 2019Article
- Irisin interaction with adipose tissue secretions by exercise training and flaxseed oil supplement.Lipids in health and disease · 2019Article
- Increase in relative skeletal muscle mass over time and its inverse association with metabolic syndrome development: a 7-year retrospective cohort study.Cardiovascular diabetology · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIrisin is a myokine implicated in lipid and glucose metabolism. The objective of this study is to examine the effect of a body weight reduction on the serum irisin level and physical indicators in obese Japanese patients without diabetes.
methodsThe subjects were 22 patients (male/female, 5/17; age, 46.1±16.0 years; body mass index [BMI], 36.9±5.0 kg/m
resultsThere were significant decreases in body weight and BMI after the intervention. Irisin before the intervention was significantly positively correlated with HOMA-IR (
conclusionBody weight reduction did not alter irisin levels. However, irisin may play important roles in fat and glucose metabolism and insulin resistance, and the effects of body weight reduction on irisin kinetics may be a key for obesity treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.