Evidence map›Paper›PMID 27766137›Full record

ReviewInternational journal of molecular epidemiology and genetics2016

Epidemiology of colorectal cancer.

Andrew R Marley, Hongmei Nan

3 registry-linked trialsAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in International journal of molecular epidemiology and genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 229 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
229citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03448302 unknown statusnot on this mapstarted 2018, after this paper: background citation

Computed Tomography Perfusion of Colorectal Cancer in Correlation With Tumor Grade

TypeobservationalSponsorAssiut UniversityRan2018 to 2019Enrolled50ConditionsColo-rectal CancerArmsComputed tomography perfusion
NCT03806244 naterminatednot on this mapstarted 2019, after this paper: background citation

Prospective Study of the Feasibility of Stereotactic Navigation in Laparoscopic Surgery for Colorectal Cancer

TypeinterventionalSponsorIHU StrasbourgRan2019 to 2022Enrolled12ConditionsColorectal CancerArmsIntraoperative acquisition (robotic c-Arm) of images
NCT06115174 phase4unknown statusnot on this mapstarted 2023, after this paper: background citation

Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer

TypeinterventionalSponsorTanta UniversityRan2023 to 2024Enrolled44ConditionsMetastatic Colorectal CarcinomaArmsPentoxifylline, FOLFOX, XELOX, Monoclonal antibodies (target therapy)
3 · Its place in the literature

Who cites it

229 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Antibiotics use and risk of colorectal neoplasia: An updated meta-analysis.International journal of colorectal disease · 2022
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  11. FXN predicts poor prognosis in colon adenocarcinoma and correlates with immune cell infiltration.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
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169 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew R MarleyDepartment of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, IN, USA.
Hongmei NanDepartment of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana UniversityIndianapolis, IN, USA; Indiana University Melvin and Bren Simon Cancer CenterIndianapolis, IN, USA.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Interdisciplinary Training in Cancer Prevention and ControlT32CA117865 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI Victoria Lee Champion, Catherine E Mosher · 2016 to 2026
$2.4M
NCATS NIH HHS UL1 TR001108NCI NIH HHS T32 CA117865
6 · The paper itself

Abstract

Colorectal cancer is currently the third deadliest cancer in the United States and will claim an estimated 49,190 U.S. lives in 2016. The purpose of this review is to summarize our current understanding of this disease, based on nationally published statistics and information presented in peer-reviewed journal articles. Specifically, this review will cover the following topics: descriptive epidemiology (including time and disease trends both in the United States and abroad), risk factors (environmental, genetic, and gene-environment interactions), screening, prevention and control, and treatment. Landmark discoveries in colorectal cancer risk factor research will also be presented. Based on the information reviewed for this report, we suggest that future U.S. public health efforts aim to increase colorectal cancer screening among African American communities, and that future worldwide colorectal cancer epidemiology studies should focus on researching nutrient-gene interactions towards the goal of improving personalized treatment and prevention strategies.

Indexed as

Colorectal cancerepidemiologyprevention and controlreviewrisk factorsscreeningtreatment

Identifiers

PMID27766137
PMCPMC5069274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.