ArticleWorld journal of emergency surgery : WJES2016
Triple diagnostics for early detection of ambivalent necrotizing fasciitis.
Article in World journal of emergency surgery : WJES, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Time is of the essence when treating necrotizing soft tissue infections: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2020Pooled it
- A validated model for early prediction of group A streptococcal aetiology in necrotising soft tissue infections using minimal patient data.BMC medicine · 2026Article
- [Necrotizing fasciitis, part 1 : Possibilities and limitations of imaging diagnostics].Radiologie (Heidelberg, Germany) · 2025Review
- Fatal facial necrotizing fasciitis: a case report highlighting diagnostic and therapeutic challenges.Oxford medical case reports · 2025Article
- Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling.Medicina (Kaunas, Lithuania) · 2025Article
- Treatment and clinical outcomes in lower extremity necrotizing soft tissue infection.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Optimization and advances in negative pressure wound therapy for the management of necrotizing fasciitis in the upper limb.World journal of orthopedics · 2025Article
- [Necrotizing fasciitis].Chirurgie (Heidelberg, Germany) · 2024Review
- Socioeconomic status affects amputation and mortality rates in necrotizing fasciitis patients.International orthopaedics · 2024Article
- [Necrotizing soft tissue infections].Die Anaesthesiologie · 2024Review
- No role for standard imaging workup of patients with clinically evident necrotizing soft tissue infections: a national retrospective multicenter cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Diagnostic Key Points and Surgical Management of Necrotizing Fasciitis: A Retrospective Study.The international journal of lower extremity wounds · 2024Article
- [Clinical efficacy of antibiotic bone cement combined with vacuum sealing drainage in treating diabetes mellitus complicated with necrotizing fasciitis].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Observational
- Necrotising fasciitis: a case series set in rural Australia.Journal of surgical case reports · 2023Article
- Prognostic factors for intraoperative detection of necrotizing fasciitis in severe soft tissue infections.PloS one · 2023Article
- Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study.Journal of hand and microsurgery · 2022Article
- Necrotizing Soft Tissue Infections of the Perineum.Clinics in colon and rectal surgery · 2022Review
- The impact of operative time on the outcomes of necrotizing soft tissue infections: a multicenter cohort study.BMC surgery · 2022Article
- Article
- Necrotizing fasciitis, causative agents and management: a five-year retrospective study in two tertiary care hospitals in Central Malaysia.International orthopaedics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing fasciitis is an uncommon, rapidly progressive and potential lethal condition. Over the last decade time to surgery decreased and outcome improved, most likely due to increased awareness and more timely referral. Early recognition is key to improve mortality and morbidity. However, early referral frequently makes it a challenge to recognize this heterogeneous disease in its initial stages. Signs and symptoms might be misleading or absent, while the most prominent skin marks might be in discrepancy with the position of the fascial necrosis. Gram staining and especially fresh frozen section histology might be a useful adjunct.
methodsRetrospective analysis of 3 year period. Non-transferred patients who presented with suspected necrotizing fasciitis are included. ASA classification was determined. Mortality was documented.
resultsIn total, 21 patients are included. Most patients suffered from severe comorbidities. In 11 patients, diagnoses was confirmed based on intra-operative macroscopic findings. Histology and/or microbiotic findings resulted in 6/10 remaining patients in a change in treatment strategy. In total, 17 patients proved to suffer necrotizing fasciitis. In the cohort series 2 patients died due to necrotizing fasciitis.
conclusionIn the early phases of necrotizing fasciitis, clinical presentation can be ambivalent. In the present cohort, triple diagnostics consisting of an incisional biopsy with macroscopic, histologic and microbiotic findings was helpful in timely identification of necrotizing fasciitis.
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