Evidence map›Paper›PMID 27766078›Full record

ArticleFrontiers in neuroinformatics2016

Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling.

Angel Lareo, Caroline G Forlim, Reynaldo D Pinto, Pablo Varona, Francisco de Borja Rodriguez

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angel LareoGrupo de Neurocomputación Biológica, Departamento de Ingeniería Informática, Escuela Politécnica superior, Universidad Autónoma de Madrid Madrid, Spain.
Caroline G ForlimDepartment of Data Analysis, Faculty of Psychology and Educational Sciences, Ghent University Ghent, Belgium.
Reynaldo D PintoLaboratory of Neurodynamics/Neurobiophysics, Department of Physics and Interdisciplinary Sciences, Institute of Physics of São Carlos, Universidade de São Paulo São Paulo, Brazil.
Pablo VaronaGrupo de Neurocomputación Biológica, Departamento de Ingeniería Informática, Escuela Politécnica superior, Universidad Autónoma de Madrid Madrid, Spain.
Francisco de Borja RodriguezGrupo de Neurocomputación Biológica, Departamento de Ingeniería Informática, Escuela Politécnica superior, Universidad Autónoma de Madrid Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox.

Indexed as

computational biologyelectric fishinformation theoryneuroinformaticssignal processing

Identifiers

PMID27766078
PMCPMC5052257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.