ArticleScientific reports2016
Extraversion and neuroticism related to the resting-state effective connectivity of amygdala.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- The mediating effect of neuroticism on the association between brain signal variability in the prefrontal cortex and depression among healthy individuals.Brain imaging and behavior · 2026Article
- Neuroticism heterogeneity through item-level associations in resting-state functional connectivity.Communications biology · 2025Article
- Neuroticism and openness exhibit an anti-correlation pattern to dissociable default mode network: using resting connectivity and structural equation modeling analysis.Brain imaging and behavior · 2024Article
- Neuroimaging Genomics a Predictor of Major Depressive Disorder (MDD).Molecular neurobiology · 2024Review
- Combined effects of neuroticism and negative emotional context on spontaneous EEG dynamics.Social cognitive and affective neuroscience · 2024Article
- Top-down control of vestibular inputs by the dorsolateral prefrontal cortex.Experimental brain research · 2023Article
- Stronger functional network connectivity and social support buffer against negative affect during the COVID-19 outbreak and after the pandemic peak.Neurobiology of stress · 2021Article
- The manifestation of individual differences in sensitivity to punishment during resting state is modulated by eye state.Cognitive, affective & behavioral neuroscience · 2021Article
- The Effects of Tryptamine Psychedelics in the Brain: A meta-Analysis of Functional and Review of Molecular Imaging Studies.Frontiers in pharmacology · 2021Review
- Resting-State Functional Connectivity Associated With Extraversion and Agreeableness in Adolescence.Frontiers in behavioral neuroscience · 2021Article
- Robust prediction of individual personality from brain functional connectome.Social cognitive and affective neuroscience · 2020Article
- Article
- Inward versus reward: white matter pathways in extraversion.Personality neuroscience · 2019Article
- Personality Profiles Are Associated with Functional Brain Networks Related to Cognition and Emotion.Scientific reports · 2018Article
- Association between amygdala neurokinin-1 receptor availability and anxiety-related personality traits.Translational psychiatry · 2018Article
- Resting-state functional brain connectivity best predicts the personality dimension of openness to experience.Personality neuroscience · 2018Article
- Predicting personality from network-based resting-state functional connectivity.Brain structure & function · 2018Article
- Resting-state functional connectivity predicts neuroticism and extraversion in novel individuals.Social cognitive and affective neuroscience · 2018Article
- Article
- Association between Neuroticism and Emotional Face Processing.Scientific reports · 2017Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The amygdala plays a key role in emotion processing. Its functional connectivity with other brain regions has been extensively demonstrated to be associated with extraversion and neuroticism. However, how the amygdala affects other regions and is affected by others within these connectivity patterns associated with extraversion and neuroticism remains unclear. To address this issue, we investigated the effective connectivity of the amygdala using Granger causality analysis on the resting-state functional magnetic resonance imaging data of 70 participants. Results showed that extraversion was positively correlated with the influence from the right inferior occipital gyrus (IOG) to the left amygdala, and from the bilateral IOG to the right amygdala; such result may represent the neural correlates of social interactions in extraverts. Conversely, neuroticism was associated with an increased influence from right amygdala to right middle frontal gyrus and a decreased influence from right precuneus to right amygdala. This influence might affect the modulations of cognitive regulation function and self-referential processes in neurotic individuals. These findings highlight the importance of the causal influences of amygdala in explaining the individual differences in extraversion and neuroticism, and offer further insights into the specific neural networks underlying personality.
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