Evidence map›Paper›PMID 27765810›Full record

ArticleG3 (Bethesda, Md.)2016

Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers.

Andrew P Morgan, John P Didion, Anthony G Doran, James M Holt, Leonard McMillan, Thomas M Keane, Fernando Pardo-Manuel de Villena

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Molecular Evolution across Mouse Spermatogenesis.Molecular biology and evolution · 2022
    Article
  5. Article
  6. Population Genomics of the House Mouse and the Brown Rat.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  7. A High Quality Genome forG3 (Bethesda, Md.) · 2018
    Article
  8. Review
  9. Sequence and Structural Diversity of Mouse Y Chromosomes.Molecular biology and evolution · 2017
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew P MorganDepartment of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599-7264.ORCID 0000-0003-1942-4543
John P DidionDepartment of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599-7264.ORCID 0000-0002-8111-6261
Anthony G DoranWellcome Trust Sanger Institute, Cambridge, CB10 1HH, United Kingdom.
James M HoltDepartment of Computer Science, University of North Carolina, Chapel Hill, North Carolina 27599-3175.
Leonard McMillanDepartment of Computer Science, University of North Carolina, Chapel Hill, North Carolina 27599-3175.
Thomas M KeaneWellcome Trust Sanger Institute, Cambridge, CB10 1HH, United Kingdom.
Fernando Pardo-Manuel de VillenaDepartment of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599-7264 fernando@med.unc.edu.ORCID 0000-0002-5738-5795

Funding

Unlocking Zika Virus Immune Control and Pathogenesis with the Collaborative CrossU19AI100625 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HEISE, MARK T · 2012 to 2021
$36.6M
UNC and PERLEGEN, IncP50GM076468 · NIGMS · JACKSON LABORATORY · PI GRABER, JOEL H · 2006 to 2015
$31.0M
UNC Predoc Training Progr in Bioinformatics/Comp BiologyT32GM067553 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELSTON, TIMOTHY C · 2005 to 2019
$2.5M
Effects of advanced paternal age on germline genome stabilityF30MH103925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, ANDREW PARKER · 2014 to 2017
$151k
Biotechnology and Biological Sciences Research Council BB/M000281/1Medical Research Council MR/L007428/1NIAID NIH HHS U19 AI100625NIGMS NIH HHS P50 GM076468NIGMS NIH HHS T32 GM067553NIMH NIH HHS F30 MH103925Wellcome Trust
6 · The paper itself

Abstract

Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ, of Mus musculus domesticus origin. These two inbred strains were selected based on their geographic origin, karyotype, and use in ongoing research. We generated 14× and 18× coverage sequence, respectively, and discovered over 1.1 million novel variants, most of which are private to one of these strains. This report expands the number of wild-derived inbred genomes in the Mus genus from six to eight. The sequence variation can be accessed via an online query tool; variant calls (VCF format) and alignments (BAM format) are available for download from a dedicated ftp site. Finally, the sequencing data have also been stored in a lossless, compressed, and indexed format using the multi-string Burrows-Wheeler transform. All data can be used without restriction.

Indexed as

DiploidyGenomeAnimalsAnimals, WildFemaleGenetic VariationGenomicsHigh-Throughput Nucleotide SequencingMaleMiceMice, Inbred StrainsPhylogenyinbred mouse strainskaryotype evolutionRobertsonian translocationswild-derived mouse strains

Identifiers

PMID27765810
PMCPMC5144988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.