ArticleAmerican journal of physiology. Heart and circulatory physiology2016
Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition.
Article in American journal of physiology. Heart and circulatory physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Monoterpenes in Vascular Function: A Review of Bioactivity and Mechanisms of Action.International journal of molecular sciences · 2025Review
- Molasses-Based Block Supplements for Cattle Fed Endophyte-Infected Tall Fescue (Animals : an open access journal from MDPI · 2025Article
- Bidirectional TRP/L Type CaBiomolecules · 2023Article
- Temperature-dependent contractility of rat tunica dartos muscle: Contribution of cold, menthol-sensitive TRPM8.BBA advances · 2023Article
- General anaesthesia-related complications of gut motility with a focus on cholinergic mechanisms, TRP channels and visceral pain.Frontiers in physiology · 2023Article
- TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β-catenin signalling.British journal of pharmacology · 2023Article
- The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances.Frontiers in molecular neuroscience · 2022Review
- Influence of Cold-TRP Receptors on Cold-Influenced Behaviour.Pharmaceuticals (Basel, Switzerland) · 2021Article
- The cold receptor TRPM8 activation leads to attenuation of endothelium-dependent cerebral vascular functions during head cooling.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Current Knowledge on the Vascular Effects of Menthol.Frontiers in physiology · 2020Review
- TRPM8 facilitates proliferation and immune evasion of esophageal cancer cells.Bioscience reports · 2019Article
- 1,8-Cineole blocks voltage-gated L-type calcium channels in tracheal smooth muscle.Pflugers Archiv : European journal of physiology · 2018Article
- Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers.PLoS neglected tropical diseases · 2018Article
- Cellular and Molecular Targets of Menthol Actions.Frontiers in pharmacology · 2017Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Transient receptor potential melastatin 8 (TRPM8) is the principal cold and menthol receptor channel. Characterized primarily for its cold-sensing role in sensory neurons, it is expressed and functional in several nonneuronal tissues, including vasculature. We previously demonstrated that menthol causes variable mechanical responses (vasoconstriction, vasodilatation, or biphasic reactions) in isolated arteries, depending on vascular tone. Here we aimed to dissect the specific ion channel mechanisms and corresponding Ca
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.