Evidence map›Paper›PMID 27765017›Full record

ArticleBMC infectious diseases2016

High third-generation cephalosporin resistant Enterobacteriaceae prevalence rate among neonatal infections in Dakar, Senegal.

Sebastien Breurec, Coralie Bouchiat, Jean-Marie Sire, Olivier Moquet, Raymond Bercion, Moussa Fafa Cisse, Philippe Glaser, Ousmane Ndiaye, Sidy Ka, Helene Salord and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Antibiotic regimens for early-onset neonatal sepsis.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Antibiotic regimens for late-onset neonatal sepsis.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Pooled it
  5. Article
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  11. Population Diversity of Antibiotic ResistantFrontiers in microbiology · 2022
    Article
  12. Observational
  13. Article
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  15. Article
  16. Detection ofIranian journal of microbiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Sebastien BreurecInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal. sbreurec@gmail.com.
Coralie BouchiatInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Jean-Marie SireInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Olivier MoquetInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Raymond BercionInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Moussa Fafa CisseHôpital des Enfants Albert Royer, Laboratoire de Bactériologie, Avenue Cheikh Anta Diop, Dakar, Senegal.
Philippe GlaserInstitut Pasteur, Unité de Biologie des Bactéries pathogènes à Gram-positif, 25-28 Rue du Dr Roux, 75015, Paris, France.
Ousmane NdiayeDépartement de Pédiatrie, Centre Hospitalier Abass Ndao, BP 15872, Dakar, Senegal.
Sidy KaDépartement de Pédiatrie, Hôpital Principal, 1 avenue Nelson Mandela, BP3006, Dakar, Senegal.
Helene SalordHôpital de la Croix-Rousse, Laboratoire de Bactériologie, 103 Grande rue de la Croix-Rousse, 69317, Lyon, France.
Abdoulaye SeckInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Haby Signate SyDépartement de Pédiatrie, Hôpital des Enfants Albert Royer, Avenue Cheikh Anta Diop, Dakar, Senegal.
Remy MichelInstitut Pasteur de Dakar, Unité d'Epidémiologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Benoit GarinInstitut Pasteur, Laboratoire de Bactériologie, 36 Avenue Pasteur, BP220, Dakar, Senegal.
Institut Pasteur de Dakar · SNCentre Hospitalier National Universitaire de Fann · SNCheikh Anta Diop University · SNHôpital de la Croix-Rousse · FRHôpital Principal de Dakar · SNInstitut Pasteur · FRUniversité des Antilles · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonatal infection constitutes one of Senegal's most important public health problems, with a mortality rate of 41 deaths per 1,000 live births.

methodsBetween January 2007 and March 2008, 242 neonates with suspected infection were recruited at three neonatal intensive care units in three major tertiary care centers in Dakar, the capital of Senegal. Neonatal infections were confirmed by positive bacterial blood or cerebrospinal fluid culture. The microbiological pattern of neonatal infections and the antibiotic susceptibility of the isolates were characterized. In addition, the genetic basis for antibiotic resistance and the genetic background of third-generation cephalosporin-resistant (3GC-R) Enterobacteriaceae were studied.

resultsA bacteriological infection was confirmed in 36.4 % (88/242) of neonates: 22.7 % (30/132) during the early-onset and 52.7 % (58/110) during the late-onset periods (p > 0.20). Group B streptococci accounted for 6.8 % of the 88 collected bacterial isolates, while most of them were Enterobacteriaceae (n = 69, 78.4 %). Of these, 55/69 (79.7 %) were 3GC-R. The bla

conclusionsMeasures should be taken to prevent nosocomial infections and the selection of resistant bacteria.

Indexed as

beta-Lactamasesbeta-Lactam ResistanceCephalosporinsEnterobacter cloacaeEnterobacteriaceaeEnterobacteriaceae InfectionsFemaleHumansInfant, NewbornKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsSenegalTertiary Care CentersTreatment Outcomebeta-LactamasesCephalosporinsAfricaAntimicrobial resistanceCTX-M-15Neonatal infectionsThird-generation cephalosporin-resistant Enterobacteriaceae

Identifiers

PMID27765017
PMCPMC5072384
OpenAlexW2533022445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.