Evidence map›Paper›PMID 27764725›Full record

Trial reportThe Journal of nutritional biochemistry2016

Drinks containing anthocyanin-rich blackcurrant extract decrease postprandial blood glucose, insulin and incretin concentrations.

Monica L Castro-Acosta, Leanne Smith, Rosalind J Miller, Danielle I McCarthy, Jonathan A Farrimond, Wendy L Hall

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutritional biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03184064 nacompletednot on this mapstarted 2017, after this paper: background citation

Acute Effects of Blackcurrant and Citrus Polyphenol Extracts on Postprandial Glycaemia: The Glu-FX Study

TypeinterventionalSponsorLucozade Ribena SuntoryRan2017 to 2018Enrolled32ConditionsPostprandial PeriodArmsBlackcurrant extract (low dose), Placebo, Citrus extract (low dose), Blackcurrant extract (high dose), Blackcurrant and citrus extracts (low dose / low dose)
NCT03572296 nacompletednot on this mapstarted 2018, after this paper: background citation

Effect of Drinks Containing Fruit Polyphenol Extracts and Fibre on Postprandial Glycaemia. The Glu-MIX Study

TypeinterventionalSponsorLucozade Ribena SuntoryRan2018 to 2019Enrolled38ConditionsPostprandial PeriodArmsPlacebo, Polyphenol and fibre, Fibre
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Trial
  4. Trial
  5. Blackcurrant (The British journal of nutrition · 2021
    Trial
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  7. Trial
  8. Review
  9. Review
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  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
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  18. Review
  19. Article
  20. Nutritional strategies to attenuate postprandial glycemic response.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Monica L Castro-AcostaDiabetes & Nutritional Sciences Division, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
Leanne SmithDiabetes & Nutritional Sciences Division, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
Rosalind J MillerGlaxoSmithKline Services Unlimited, GSK House, 980 Great West Road, Middlesex, TW8 9GS, UK.
Danielle I McCarthySuntory Beverage and Food Europe Ltd, 2 Longwalk Road, Stockley Park, Uxbridge UB11 1BA, UK.
Jonathan A FarrimondSuntory Beverage and Food Europe Ltd, 2 Longwalk Road, Stockley Park, Uxbridge UB11 1BA, UK.
Wendy L HallDiabetes & Nutritional Sciences Division, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK. Electronic address: wendy.hall@kcl.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

Blackcurrants are rich in polyphenolic glycosides called anthocyanins, which may inhibit postprandial glycemia. The aim was to determine the dose-dependent effects of blackcurrant extract on postprandial glycemia. Men and postmenopausal women (14M, 9W, mean age 46 years, S.D.=14) were enrolled into a randomized, double-blind, crossover trial. Low sugar fruit drinks containing blackcurrant extract providing 150-mg (L-BE), 300-mg (M-BE) and 600-mg (H-BE) total anthocyanins or no blackcurrant extract (CON) were administered immediately before a high-carbohydrate meal. Plasma glucose, insulin and incretins (GIP and GLP-1) were measured 0-120min, and plasma 8-isoprostane F

Indexed as

BeveragesAdultAnthocyaninsBlood GlucoseCross-Over StudiesDiet, Carbohydrate LoadingDiet, Carbohydrate-RestrictedDouble-Blind MethodFemaleFruitFunctional FoodHumansHyperglycemiaHyperinsulinismHypoglycemic AgentsIncretinsAnthocyaninsBlood GlucoseHypoglycemic AgentsIncretinsPlant ExtractsAnthocyaninsBerriesIncretinsInsulinPolyphenolsPostprandial glycemiaRandomized controlled trial

Identifiers

PMID27764725
PMCPMC5170886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.