Evidence map›Paper›PMID 27764692›Full record

Trial reportJournal of psychiatric research2017

Memory performance predicts recurrence of mania in bipolar disorder following psychotherapy: A preliminary study.

Isabelle E Bauer, Martin Hautzinger, Thomas D Meyer

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychiatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Isabelle E BauerDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, TX, United States.
Martin HautzingerDepartment of Psychology and Psychotherapy, University of Tübingen, Germany.
Thomas D MeyerDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, TX, United States. Electronic address: Thomas.D.Meyer@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USUniversity of St. Thomas - Texas · USUniversity of Tübingen · DE

Funding

Searching for Endophenotypes of Bipolar DisorderR01MH085667 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SOARES, JAIR C · 2012 to 2016
$3.0M
NIMH NIH HHS R01 MH085667
6 · The paper itself

Abstract

objectiveCognitive complaints are common features of bipolar disorder (BD). Not much is, however, known about the potential moderator effects of these factors on the outcome of talking therapies. The goal of our study was to explore whether learning and memory abilities predict risk of recurrence of mood episodes or interact with a psychological intervention.

methodWe analyzed data collected as part of a clinical trial evaluating relapse rates following Cognitive Behavioral Therapy (CBT) and Supportive Therapy (ST) (Meyer and Hautzinger, 2012). We included cognitive (Auditive Verbal Learning Test, general intelligence - Leistungsprüfsystem) and clinical measures from 76 euthymic patients with BD randomly assigned to either 9 months of CBT or ST and followed up for 2 years.

resultsSurvival analyses including treatment condition, AVLT measures, and general intelligence revealed that recurrence of mania was predicted by verbal free recall. The significant interaction between therapy condition and free recall indicated that while in CBT recurrence of mania was unrelated to free recall performance, in ST patients with a better free recall were more likely to remain euthymic, and those with a poorer free recall were less likely to remain mania-free.

conclusionsThese findings constitute first evidence that, when considering treatment outcome in BD, differences in verbal free recall might interact with the kind of psychotherapy provided. More research is needed to determine what other areas of cognitive functioning are related to outcome in psychological interventions.

Indexed as

MemoryPsychotherapyAdultBipolar DisorderFemaleFollow-Up StudiesHumansIntelligenceInterview, PsychologicalMaleOdds RatioPrognosisProportional Hazards ModelsPsychiatric Status Rating ScalesPsychological TestsRecurrenceBipolar disorderCognitivePsychotherapyRecurrence

Identifiers

PMID27764692
PMCPMC5125875
OpenAlexW2530812091

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.