Evidence map›Paper›PMID 27764107›Full record

ArticlePloS one2016

Development of a Web-Based Clinical Decision Support System for Drug Prescription: Non-Interventional Naturalistic Description of the Antipsychotic Prescription Patterns in 4345 Outpatients and Future Applications.

Sofian Berrouiguet, Maria Luisa Barrigón, Sara A Brandt, Santiago Ovejero-García, Raquel Álvarez-García, Juan Jose Carballo, Philippe Lenca, Philippe Courtet, MEmind Study Group, Enrique Baca-García

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  5. Ecological Momentary Assessment for Monitoring Risk of Suicide Behavior.Current topics in behavioral neurosciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Sofian BerrouiguetDepartment of Psychiatry and Emergency, Brest Medical University Hospital, Brest, France.
Maria Luisa BarrigónDepartment of Psychiatry at Fundación Jimenez Diaz Hospital, Madrid, Spain.
Sara A BrandtDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, United States of America.
Santiago Ovejero-GarcíaDepartment of Psychiatry at Fundación Jimenez Diaz Hospital, Madrid, Spain.
Raquel Álvarez-GarcíaDepartment of Psychiatry, University Hospital Rey Juan Carlos, Móstoles, Madrid, Spain.
Juan Jose CarballoDepartment of Psychiatry at Fundación Jimenez Diaz Hospital, Madrid, Spain.
Philippe LencaLogics in Uses, Social Science and Information Science department, Telecom Bretagne, Plouzané, France.
Philippe CourtetINSERM U888, Department of Psychiatry, Montpellier University Hospital, Montpellier, France.
MEmind Study Group
Enrique Baca-GarcíaDepartment of Psychiatry, IIS-Jimenez Diaz Foundation, Madrid, Spain.
Hospital Universitario Fundación Jiménez Díaz · ESCentro de Investigación Biomédica en Red de Salud Mental · ESCentre Hospitalier Régional Universitaire de Brest · FRHospital Universitario Rey Juan Carlos · ESIcahn School of Medicine at Mount Sinai · USInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe emergence of electronic prescribing devices with clinical decision support systems (CDSS) is able to significantly improve management pharmacological treatments. We developed a web application available on smartphones in order to help clinicians monitor prescription and further propose CDSS.

methodA web application (www.MEmind.net) was developed to assess patients and collect data regarding gender, age, diagnosis and treatment. We analyzed antipsychotic prescriptions in 4345 patients attended in five Psychiatric Community Mental Health Centers from June 2014 to October 2014. The web-application reported average daily dose prescribed for antipsychotics, prescribed daily dose (PDD), and the PDD to defined daily dose (DDD) ratio.

resultsThe MEmind web-application reported that antipsychotics were used in 1116 patients out of the total sample, mostly in 486 (44%) patients with schizophrenia related disorders but also in other diagnoses. Second generation antipsychotics (quetiapine, aripiprazole and long-acting paliperidone) were preferably employed. Low doses were more frequently used than high doses. Long acting paliperidone and ziprasidone however, were the only two antipsychotics used at excessive dosing. Antipsychotic polypharmacy was used in 287 (26%) patients with classic depot drugs, clotiapine, amisulpride and clozapine.

conclusionsIn this study we describe the first step of the development of a web application that is able to make polypharmacy, high dose usage and off label usage of antipsychotics visible to clinicians. Current development of the MEmind web application may help to improve prescription security via momentary feedback of prescription and clinical decision support system.

Indexed as

Decision Support Systems, ClinicalDrug PrescriptionsAdolescentAdultAgedAntipsychotic AgentsCommunity Mental Health CentersFemaleHumansInappropriate PrescribingInternetMaleMiddle AgedOutpatientsPaliperidone PalmitatePiperazinesAntipsychotic AgentsPaliperidone PalmitatePiperazinesThiazolesziprasidone

Identifiers

PMID27764107
PMCPMC5072715
OpenAlexW2536736867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.