Evidence map›Paper›PMID 27763552›Full record

ArticleViruses2016

Maporal Hantavirus Causes Mild Pathology in Deer Mice (Peromyscus maniculatus).

Amanda McGuire, Kaitlyn Miedema, Joseph R Fauver, Amber Rico, Tawfik Aboellail, Sandra L Quackenbush, Ann Hawkinson, Tony Schountz

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Genetic characterization of a hantavirus isolated from Heilongjiang province, China.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Amanda McGuireArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. amanda.mcguire@colostate.edu.
Kaitlyn MiedemaArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. kaitlyn.miedema@colostate.edu.
Joseph R FauverArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. joseph.fauver@colostate.edu.
Amber RicoSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, NE 68583, USA. arico3@unl.edu.
Tawfik AboellailArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. tawfik.aboellail@colostate.edu.
Sandra L QuackenbushDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. sandra.quackenbush@colostate.edu.
Ann HawkinsonSchool of Biological Sciences, University of Northern Colorado, Greeley, CO 80639, USA. ann.hawkinson@unco.edu.
Tony SchountzArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. tony.schountz@colostate.edu.
Colorado State University · USUniversity of Nebraska–Lincoln · USUniversity of Northern Colorado · US

Funding

Deer Mice as Tools for Infectious Disease ResearchR15AI054461 · NIAID · UNIVERSITY OF NORTHERN COLORADO · PI HAWKINSON, ANN · 2006 to 2013
$598k
Factors governing immunopathology, persistence or clearance of New World hantavirusesR56AI110535 · NIAID · COLORADO STATE UNIVERSITY · PI SCHOUNTZ, WILLIAM A · 2016 to 2016
$373k
NIAID NIH HHS R15 AI054461NIAID NIH HHS R56 AI110535
6 · The paper itself

Abstract

Rodent-borne hantaviruses can cause two human diseases with many pathological similarities: hantavirus cardiopulmonary syndrome (HCPS) in the western hemisphere and hemorrhagic fever with renal syndrome in the eastern hemisphere. Each virus is hosted by specific reservoir species without conspicuous disease. HCPS-causing hantaviruses require animal biosafety level-4 (ABSL-4) containment, which substantially limits experimental research of interactions between the viruses and their reservoir hosts. Maporal virus (MAPV) is a South American hantavirus not known to cause disease in humans, thus it can be manipulated under ABSL-3 conditions. The aim of this study was to develop an ABSL-3 hantavirus infection model using the deer mouse (

Indexed as

Adaptive ImmunityDisease Models, AnimalAnimalsAnimal StructuresAntibodies, NeutralizingAntibodies, ViralCytokinesHantavirus InfectionsHistocytochemistryOrthohantavirusPeromyscusRNA, ViralTime FactorsAntibodies, NeutralizingAntibodies, ViralCytokinesRNA, Viraldeer micehantavirusMaporal virusreservoirzoonoses

Identifiers

PMID27763552
PMCPMC5086618
OpenAlexW2534733506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.