ArticleScientific reports2016
Juvenile hormone regulation of female reproduction in the common bed bug, Cimex lectularius.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 87 citations in OpenAlex.
- Comparative metabolomics reveal developmental and ecological plasticity in the invasive parasite Philornis downsi (Diptera: Muscidae) from the Galapagos Islands.Journal of insect science (Online) · 2026Article
- Involvement of Taiman in juvenile hormone signaling controlling sexual maturation in a male moth.Current research in insect science · 2026Article
- Tissue-specific transcriptomic and endocrine signatures of obligatory reproductive diapause in Eurygaster integriceps.Scientific reports · 2025Article
- The GPCR A35 regulates fecundity ofFrontiers in insect science · 2025Article
- Phosphoproteomics analyses ofHeliyon · 2024Article
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- Phenomenon of reproductive plasticity in ants.Current opinion in insect science · 2024Review
- RNA Interference-Mediated Suppression of Ecdysone Signaling Inhibits Choriogenesis in Two Coleoptera Species.International journal of molecular sciences · 2024Article
- Molecular characterization of Vitellogenin-like1 gene in Sogatella furcifera (Hemiptera: Delphacidae), and its function on reproduction.Journal of insect science (Online) · 2024Article
- Dual roles of methoprene-tolerant geneFrontiers in physiology · 2024Article
- Regulation and remodeling of microbial symbiosis in insect metamorphosis.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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- Involvement of Methoprene-tolerant and Krüppel homolog 1 in juvenile hormone-mediated vitellogenesis of female Liposcelis entomophila (End.) (Psocoptera: Liposcelididae).Archives of insect biochemistry and physiology · 2023Article
- Juvenile hormone receptor Methoprene tolerant: Functions and applications.Vitamins and hormones · 2023Article
- A critical role for ecdysone response genes in regulating egg production in adult female Rhodnius prolixus.PloS one · 2023Article
- Impact of JH Signaling on Reproductive Physiology of the Classical Insect Model,International journal of molecular sciences · 2022Article
- Reproductive Outbreaks ofInternational journal of molecular sciences · 2022Article
- Article
- Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
To begin studies on reproduction in common bed bug, Cimex lectularius, we identified three genes coding for vitellogenin (Vg, a protein required for the reproductive success of insects) and studied their hormonal regulation. RNA interference studied showed that expression of Vg3 gene in the adult females is a prerequisite for successful completion of embryogenesis in the eggs laid by them. Juvenile hormone (JH) receptor, Methoprene-tolerant (Met), steroid receptor coactivator (SRC) and GATAa but not ecdysone receptor (EcR) or its partner, ultraspiracle (USP) are required for expression of Vg genes. Feeding and mating working through Vg, Met, SRC, EcR, and GATAa regulate oocyte development. Knockdown of the expression of Met, SRC, EcR, USP, BR-C (Broad-Complex), TOR (target of rapamycin), and GATAa in female adults resulted in a reduction in the number eggs laid by them. Interestingly, Kruppel homolog 1 (Kr-h1) knockdown in the adult females did not reduce their fecundity but affected the development of embryos in the eggs laid by females injected with Kr-h1 double-stranded RNA. These data suggest that JH functioning through Met and SRC regulate both vitellogenesis and oogenesis in C. lectularius. However, JH does not work through Kr-h1 but may work through transcription factors not yet identified.
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