ArticleScientific reports2016
Formaldehyde impairs transepithelial sodium transport.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Potential of Saliva in Stroke Patients: A Review.International journal of molecular sciences · 2026Review
- Metabolic regulation adapting to high methanol environment in the methylotrophic yeast Ogataea methanolica.Microbial biotechnology · 2021Article
- Article
- Ion transport mechanisms for smoke inhalation-injured airway epithelial barrier.Cell biology and toxicology · 2020Article
- Lipopolysaccharide Inhibits Alpha Epithelial Sodium Channel Expression via MiR-124-5p in Alveolar Type 2 Epithelial Cells.BioMed research international · 2020Article
- Evaluation of chemical constituents and in vitro antimicrobial, antioxidant and cytotoxicity potential of rhizome of Astilbe rivularis (Bodho-okhati), an indigenous medicinal plant from Eastern Himalayan region of India.BMC complementary and alternative medicine · 2019Article
- Novel mechanisms for crotonaldehyde-induced lung edema.Oncotarget · 2017Article
- Short Term Exposure of Sheep Tracheal Epithelium to Cigarette Smoke Extract Reduces ENaC Current: A Pilot Study.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Unsaturated oxidative formaldehyde is a noxious aldehyde in cigarette smoke that causes edematous acute lung injury. However, the mechanistic effects of formaldehyde on lung fluid transport are still poorly understood. We examined how formaldehyde regulates human epithelial sodium channels (ENaC) in H441 and expressed in Xenopus oocytes and exposed mice in vivo. Our results showed that formaldehyde reduced mouse transalveolar fluid clearance in vivo. Formaldehyde caused a dose-dependent inhibition of amiloride-sensitive short-circuit Na
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Registered trials
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