ArticleScientific reports2016
Quantitative analysis of echogenicity for patients with thyroid nodules.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Quantitative Ultrasound Grayscale Analysis and Size of Benign and Malignant Solid Thyroid Nodules.Tomography (Ann Arbor, Mich.) · 2025Article
- Quantitative Pleural Fluid Echogenicity for Differentiating Transudative From Exudative Pleural Effusions.Cureus · 2025Article
- Impact of Ultrasonographic Features Indicative of Malignancy on Tumor Advancement in Thyroid Cancer-A Single-Center Study.Cancers · 2025Article
- Article
- Does a three-degree hypoechogenicity grading improve ultrasound thyroid nodule risk stratification and affect the TI-RADS 4 category? A retrospective observational study.Archives of endocrinology and metabolism · 2023Observational
- Malignancy risk stratification of thyroid nodules according to echotexture and degree of hypoechogenicity: a retrospective multicenter validation study.Scientific reports · 2022Article
- Assessing Detection Accuracy of Computerized Sonographic Features and Computer-Assisted Reading Performance in Differentiating Thyroid Cancers.Biomedicines · 2022Article
- Non-Marked Hypoechogenic Nodules: Multicenter Study on the Thyroid Malignancy Risk Stratification and Accuracy Based on TIRADS Systems Comparison.Medicina (Kaunas, Lithuania) · 2022Article
- Computer-Analyzed Ultrasound Predictors of the Treatment Efficacy of Radiofrequency Ablation for Benign Thyroid Nodules.World journal of surgery · 2022Article
- Article
- Software-Based Analysis of the Taller-Than-Wide Feature of High-Risk Thyroid Nodules.Annals of surgical oncology · 2021Article
- Preliminary study on the application of renal ultrasonography radiomics in the classification of glomerulopathy.BMC medical imaging · 2021Article
- Risk Stratification in Patients With Follicular Neoplasm on Cytology: Use of Quantitative Characteristics and Sonographic Patterns.Frontiers in endocrinology · 2021Article
- Article
- Ultrasound malignancy risk stratification of thyroid nodules based on the degree of hypoechogenicity and echotexture.European radiology · 2020Article
- Multi-Reader Multi-Case Study for Performance Evaluation of High-Risk Thyroid Ultrasound with Computer-Aided Detection.Cancers · 2020Article
- Artificial Intelligence for Personalized Medicine in Thyroid Cancer: Current Status and Future Perspectives.Frontiers in oncology · 2020Review
- Diagnosis of thyroid nodules for ultrasonographic characteristics indicative of malignancy using random forest.BioData mining · 2020Article
- Article
- Application of deep learning to the diagnosis of cervical lymph node metastasis from thyroid cancer with CT.European radiology · 2019Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypoechogenicity has been described qualitatively and is potentially subject to intra- and inter-observer variability. The aim of this study was to clarify whether quantitative echoic indexes (EIs) are useful for the detection of malignant thyroid nodules. Overall, 333 participants with 411 nodules were included in the final analysis. Quantification of echogenicity was performed using commercial software (AmCAD-UT; AmCad BioMed, Taiwan). The coordinates of three defined regions, the nodule, thyroid parenchyma, and strap muscle regions, were recorded in the database separately for subsequent analysis. And the results showed that ultrasound echogenicity (US-E), as assessed by clinicians, defined hypoechogenicity as an independent factor for malignancy. The EI, adjusted EI (EI
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