Evidence map›Paper›PMID 27761790›Full record

ReviewReviews in endocrine & metabolic disorders2017

Adrenal disorders: Is there Any role for vitamin D?

Giacomo Tirabassi, Gianmaria Salvio, Barbara Altieri, Cristina L Ronchi, Silvia Della Casa, Alfredo Pontecorvi, Giancarlo Balercia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Oxidative Stress, Testosterone, Cortisol, and Vitamin D: Differences in Professional Soccer Players of African and Caucasian Origin.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Article
  7. Article
  8. Review
  9. The effects of mitotane and 1α,25-dihydroxyvitamin DJournal of endocrinological investigation · 2020
    Article
  10. Vitamin D testing: advantages and limits of the current assays.European journal of clinical nutrition · 2020
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Giacomo TirabassiDivision of Endocrinology, Department of Clinical and Molecular Sciences, Umberto I Hospital, Polytechnic University of Marche, Ancona, Italy. tirabassg@yahoo.it.ORCID 0000-0003-0787-7051
Gianmaria SalvioDivision of Endocrinology, Department of Clinical and Molecular Sciences, Umberto I Hospital, Polytechnic University of Marche, Ancona, Italy.
Barbara AltieriDivision of Endocrinology and Metabolic Diseases, Catholic University of the Sacred Heart, Rome, Italy.
Cristina L RonchiDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany.
Silvia Della CasaDivision of Endocrinology and Metabolic Diseases, Catholic University of the Sacred Heart, Rome, Italy.
Alfredo PontecorviDivision of Endocrinology and Metabolic Diseases, Catholic University of the Sacred Heart, Rome, Italy.
Giancarlo BalerciaDivision of Endocrinology, Department of Clinical and Molecular Sciences, Umberto I Hospital, Polytechnic University of Marche, Ancona, Italy.
Marche Polytechnic University · ITUniversità Cattolica del Sacro Cuore · ITUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An emerging branch of research is examining the linkage between Vitamin D and nonskeletal disorders, including endocrine diseases. In this regard, a still little studied aspect concerns the involvement of vitamin D in adrenal gland disorders. Adrenal gland disorders, which might be theoretically affected by vitamin D unbalance, include adrenal insufficiency, Cushing's syndrome, adrenocortical tumors and hyperaldosteronism. In this review, we provide an updated document, which tries to collect and discuss the limited evidence to be found in the literature about the relationship between vitamin D and adrenal disorders. We conclude that there is insufficient evidence proving a causal relationship between vitamin D levels and adrenal disorders. Evidence coming from cross-sectional clinical studies can hardly clarify what comes first between vitamin D unbalance and adrenal disease. On the other hand, longitudinal studies monitoring the levels of vitamin D in patients with adrenal disorders or, conversely, the possible development of adrenal pathologies in subjects affected by impaired vitamin D levels would be able to elucidate this still unclear issue.

Indexed as

Adrenal Cortex HormonesAdrenal Gland DiseasesAdrenal GlandsAdrenal InsufficiencyCross-Sectional StudiesCushing SyndromeHumansHyperaldosteronismVitamin DVitamin D DeficiencyAdrenal Cortex HormonesVitamin DAdrenal gland disordersAdrenal insufficiencyAdrenal tumorsCushing’s syndromeHyperaldosteronismVitamin D

Identifiers

PMID27761790
OpenAlexW2537701016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.