ArticleEuropean radiology2017
Computed tomography features and predictive findings of ruptured gastrointestinal stromal tumours.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Exploring nanotechnology solutions for improved outcomes in gastrointestinal stromal tumors.Heliyon · 2024Review
- Achieving safe and high-performance gastrointestinal tract spectral CT imaging with small-molecule lanthanide complex.Biomaterials research · 2023Article
- Relationship between multi-slice computed tomography features and pathological risk stratification assessment in gastric gastrointestinal stromal tumors.World journal of gastrointestinal oncology · 2023Article
- Gastrointestinal stromal tumors: a comprehensive radiological review.Japanese journal of radiology · 2022Review
- Article
- Assessment of morphological CT imaging features for the prediction of risk stratification, mutations, and prognosis of gastrointestinal stromal tumors.European radiology · 2021Article
- Preoperative prediction of gastrointestinal stromal tumors with high Ki-67 proliferation index based on CT features.Annals of translational medicine · 2021Article
- Preoperative CT feature of incomplete overlying enhancing mucosa as a high-risk predictor in gastrointestinal stromal tumors of the stomach.European radiology · 2021Article
- Primary gastric squamous cell carcinoma presenting as a large submucosal mass: A case report and literature review.Medicine · 2020Article
- Difference of computed tomographic characteristic findings between gastric and intestinal gastrointestinal stromal tumors.Japanese journal of radiology · 2020Article
- Multiparametric MRI andEuropean radiology · 2020Article
- Current and Potential Applications of Artificial Intelligence in Gastrointestinal Stromal Tumor Imaging.Contrast media & molecular imaging · 2020Review
- Association between CT imaging features and KIT mutations in small intestinal gastrointestinal stromal tumors.Scientific reports · 2019Article
- The roles of CT and EUS in the preoperative evaluation of gastric gastrointestinal stromal tumors larger than 2 cm.European radiology · 2019Article
- Tumor heterogeneity in gastrointestinal stromal tumors of the small bowel: volumetric CT texture analysis as a potential biomarker for risk stratification.Cancer imaging : the official publication of the International Cancer Imaging Society · 2018Article
- Clinicopathological Features and Prognosis of Primary GISTs with Tumor Rupture in the Real World.Annals of surgical oncology · 2018Article
- Gastrointestinal stromal tumors: A multidisciplinary challenge.World journal of gastroenterology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the CT features of ruptured GISTs and factors that might be predictive of rupture through comparison with CTs taken prior to rupture and CTs of non-ruptured GIST.
methodsForty-nine patients with ruptured GIST and forty-nine patients with non-ruptured GIST matched by age, gender and location were included. Clinical data including pharmacotherapy were reviewed. The imaging features were analyzed. Prior CT obtained before rupture were evaluated.
resultsThe most common location of ruptured GIST was small bowel with mean size of 12.1 cm. Ruptured GIST commonly showed wall defects, >40 % eccentric necrosis, lobulated shaped, air density in mass, pneumoperitoneum, peritonitis, hemoperitoneum and ascites (p < 0.001-0.030). Twenty-seven of 30 patients with follow up imaging received targeted therapy. During follow-up, thickness of the tumour wall decreased. Increase in size and progression of necrosis were common during targeted therapy (p = 0.017). Newly developed ascites, peritonitis and hemoperitoneum was more common (p < 0.001-0.036).
conclusionRuptured GISTs commonly demonstrate large size, >40 % eccentric necrosis, wall defects and lobulated shape. The progression of necrosis with increase in size and decreased wall thickness during targeted therapy may increase the risk of rupture. Rupture should be considered when newly developed peritonitis, hemoperitoneum, or ascites are noted during the follow-up. KEY POINTS: • Ruptured GISTs demonstrate large size, eccentric necrosis, wall defects, and lobulated shape. • Rupture should be considered when peritonitis or hemoperitoneum/adjacent hematoma newly appears. • Progression of necrosis with increase in size increases the risk of rupture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.