SynthesisEuropean radiology2017
Malignancy rates and diagnostic performance of the Bosniak classification for the diagnosis of cystic renal lesions in computed tomography - a systematic review and meta-analysis.
Synthesis in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Diagnostic value of percutaneous sampling in Bosniak III-IV renal cysts: a systematic review and meta-analysis.The Canadian journal of urology · 2026Pooled it
- Utilization of the modified Bosniak classification system for complex renal cysts.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Efficacy and safety of percutaneous thermal ablation in Bosniak III and IV cystic renal masses: a systematic review and meta-analysis.Diagnostic and interventional radiology (Ankara, Turkey) · 2025Pooled it
- Small Study Effects in Diagnostic Imaging Accuracy: A Meta-Analysis.JAMA network open · 2022Pooled it
- Diagnostic performance of the Bosniak classification, version 2019 for cystic renal masses: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Eosinophilic solid and cystic renal cell carcinoma: a case report of a young Ghanaian female.Journal of surgical case reports · 2026Article
- Bosniak IIF renal cysts: natural history and the impact of lesion size on progression.International urology and nephrology · 2026Observational
- Partial Nephrectomy Versus Thermal Ablation for Cystic Renal Tumors: A Registry-Based, Propensity Score Matched Analysis (UroCCR n°177).Cardiovascular and interventional radiology · 2026Article
- Article
- Clinical value of contrast-enhanced ultrasound combined with quantitative analysis in Bosniak ≥ II cystic renal masses.Abdominal radiology (New York) · 2025Article
- Urothelial carcinoma mimicking Bosniak IV cystic mass: A case report.Radiology case reports · 2025Article
- Malignant Transformation of Renal Cyst with Bosniak I Features.Diagnostics (Basel, Switzerland) · 2025Article
- Role of imaging in the diagnosis and management of mixed epithelial and stromal tumors of the kidney: Case series and comprehensive review.Radiology case reports · 2025Article
- Article
- A contrast-enhanced computed tomography-based radiomics nomogram for preoperative differentiation between benign and malignant cystic renal lesions.Translational andrology and urology · 2024Article
- Contrast enhanced ultrasound of cystic renal lesions, from diagnosis up to treatment.Clinical hemorheology and microcirculation · 2024Review
- Association between donor kidney cysts and donor and recipient outcomes after living donor kidney transplantation.Clinical transplantation · 2024Article
- The Performance of Flash Replenishment Contrast-Enhanced Ultrasound for the Qualitative Assessment of Kidney Lesions in Patients with Chronic Kidney Disease.Journal of clinical medicine · 2023Article
- 2023 UPDATE - Canadian Urological Association guideline: Management of cystic renal lesions Prior to original publication (March 2017), this guideline underwent review by the CUA Guidelines Committee, CUA members at large, and the CUA Executive Board. The 2023 updates were app roved by the CUA Guidelines Committee and CUA Executive Board.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
- Cost-effectiveness of Contrast-Enhanced Ultrasound for Diagnosis and Active Surveillance of Complex Cystic Renal Lesions.Urology practice · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically review the literature on the Bosniak classification system in CT to determine its diagnostic performance to diagnose malignant cystic lesions and the prevalence of malignancy in Bosniak categories.
methodsA predefined database search was performed from 1 January 1986 to 18 January 2016. Two independent reviewers extracted data on malignancy rates in Bosniak categories and several covariates using predefined criteria. Study quality was assessed using QUADAS-2. Meta-analysis included data pooling, subgroup analyses, meta-regression and investigation of publication bias.
resultsA total of 35 studies, which included 2,578 lesions, were investigated. Data on observer experience, inter-observer variation and technical CT standards were insufficiently reported. The pooled rate of malignancy increased from Bosniak I (3.2 %, 95 % CI 0-6.8, I
conclusionThe Bosniak classification is an accurate tool with which to stratify the risk of malignancy in renal cystic lesions. KEY POINTS: • The Bosniak classification can accurately rule out malignancy. • Specificity remains moderate at 74 % (95 % CI 64-82). • Follow-up examinations should be considered in Bosniak IIF and Bosniak II cysts. • Data on the influence of reader experience and inter-reader variability are insufficient. • Technical CT standards and publication year did not influence diagnostic performance.
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