ArticleEuropean radiology2017
Diagnosis of sub-centimetre breast lesions: combining BI-RADS-US with strain elastography and contrast-enhanced ultrasound-a preliminary study in China.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative Diagnostic Accuracy of Contrast-Enhanced Ultrasound and Shear Wave Elastography in Differentiating Benign and Malignant Lesions: A Network Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Diagnostic Value of Contrast-Enhanced Ultrasonography With SonoVue in the Differentiation of Benign and Malignant Breast Lesions: A Meta-Analysis.Technology in cancer research & treatmentPooled it
- The added value of contrast-enhanced ultrasonography to BI-RADS in the evaluation of breast lesions presenting with pathological nipple discharge.Quantitative imaging in medicine and surgery · 2026Article
- Predicting postoperative malignancy upgrading in B1-B3 breast lesions: combined utility of conventional ultrasound and contrast-enhanced ultrasound features.Quantitative imaging in medicine and surgery · 2026Article
- Exploring the Application of Contrast-Enhanced Ultrasound in ACR BI-RADS 4A Lesions (≤ 2 cm): A Prospective Multicenter Study in China.The breast journal · 2026Article
- Development and validation of a clinical-bimodal nomogram to predict the malignancy of pathologic nipple discharge.Quantitative imaging in medicine and surgery · 2025Article
- Diagnostic test of conventional ultrasonography combined with contrast-enhanced ultrasound in the subcategorization of suspicious Breast Imaging-Reporting and Data System (BI-RADS) 4 breast lesions.Translational cancer research · 2025Article
- Current status and future perspectives of contrast-enhanced ultrasound diagnosis of breast lesions.Journal of medical ultrasonics (2001) · 2024Review
- Downgrading Breast Imaging Reporting and Data System categories in ultrasound using strain elastography and computer-aided diagnosis system: a multicenter, prospective study.The British journal of radiology · 2024Article
- Contrast-enhanced ultrasound to predict malignant upgrading of atypical ductal hyperplasia.Breast cancer research : BCR · 2024Article
- Review
- Conventional ultrasound combined with contrast-enhanced ultrasound: could it be helpful for the diagnosis of thoracic wall recurrence after mastectomy?European radiology · 2023Article
- The diagnostic value of contrast-enhanced ultrasonography in breast ductal abnormalities.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Value of the strain ratio in the differential diagnosis of intraocular tumors by elastosonography: A retrospective case-control study.Indian journal of ophthalmology · 2023Article
- A Novel Nomogram Based on Imaging Biomarkers of Shear Wave Elastography, Angio Planewave Ultrasensitive Imaging, and Conventional Ultrasound for Preoperative Prediction of Malignancy in Patients with Breast Lesions.Diagnostics (Basel, Switzerland) · 2023Article
- Diagnostic value of shear wave elastography combined with super microvascular imaging for BI-RADS 3-5 nodules.Frontiers in oncology · 2023Article
- Contrast-enhanced ultrasound of granular cell tumor in breast: A case report with review of the literature.Frontiers in oncology · 2022Article
- Multi-parameter ultrasonography-based predictive model for breast cancer diagnosis.Frontiers in oncology · 2022Article
- Contrast-enhanced ultrasonography for differential diagnosis of adnexal masses.Frontiers in oncology · 2022Article
- Can strain US-elastography with strain ratio (SRE) improve the diagnostic accuracy in the assessment of breast lesions? Preliminary results.Journal of ultrasound · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the diagnostic efficacies of B-mode ultrasound (US), strain elastography (SE), contrast-enhanced ultrasound (CEUS) and the combination of these modalities for breast lesions <1 cm in size.
methodsBetween January 2013 and October 2015, 203 inpatients with 209 sub-centimetre breast lesions categorised as BI-RADS-US (Breast Imaging Reporting and Data System for Ultrasound) 3-5 were included. US, SE and CEUS were performed to evaluate each lesion. The diagnostic performances of different ultrasonic modalities were compared. The diagnostic efficacies of BI-RADS-US and our re-rating systems were also compared. The pathology findings were used as the reference standard.
resultsThe specificities of US, SE and CEUS for tumour differentiation were 17.4 %, 56.2 % and 86.0 %, respectively (P < 0.05); and the sensitivities were 100 %, 93.2 % and 93.2 % for US, SE and CEUS, respectively (P < 0.05). The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was 0.867 for original BI-RADS-US, 0.882 for BI-RADS-US combined with only SE, 0.953 for BI-RADS-US combined with only CEUS and 0.924 for BI-RADS-US combined with both SE and CEUS. The best combination was BI-RADS-US combined with only CEUS.
conclusionsEvaluating sub-centimetre breast lesions with SE and CEUS could increase the diagnostic specificity while retaining high sensitivity compared with B-mode ultrasound. KEY POINTS: • Evaluating breast lesions with SE and CEUS could increase the diagnostic specificity • SE and CEUS offer alternatives to biopsy and possibly allow shorter-interval follow-ups • BI-RADS-US combined with CEUS exhibited the best diagnostic performance.
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