Evidence map›Paper›PMID 27761598›Full record

ArticleExperimental brain research2017

Seeing the sound after visual loss: functional MRI in acquired auditory-visual synesthesia.

Zixin Yong, Po-Jang Hsieh, Dan Milea

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Neurophenomenology of induced and natural synaesthesia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Zixin YongNeuroscience and Behavioral Disorders Program, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Po-Jang HsiehNeuroscience and Behavioral Disorders Program, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. pojang.hsieh@duke-nus.edu.sg.
Dan MileaNeuroscience and Behavioral Disorders Program, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. dan.milea@snec.com.sg.
Duke-NUS Medical School · SGSingapore National Eye Center · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired auditory-visual synesthesia (AVS) is a rare neurological sign, in which specific auditory stimulation triggers visual experience. In this study, we used event-related fMRI to explore the brain regions correlated with acquired monocular sound-induced phosphenes, which occurred 2 months after unilateral visual loss due to an ischemic optic neuropathy. During the fMRI session, 1-s pure tones at various pitches were presented to the patient, who was asked to report occurrence of sound-induced phosphenes by pressing one of the two buttons (yes/no). The brain activation during phosphene-experienced trials was contrasted with non-phosphene trials and compared to results obtained in one healthy control subject who underwent the same fMRI protocol. Our results suggest, for the first time, that acquired AVS occurring after visual impairment is associated with bilateral activation of primary and secondary visual cortex, possibly due to cross-wiring between auditory and visual sensory modalities.

Indexed as

Acoustic StimulationAdultAuditory PerceptionBlindnessBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleOptic Neuropathy, IschemicOxygenPerceptual DisordersPhosphenesSynesthesiaVisual PerceptionOxygenAuditory-visualFunctional MRIIschemic optic neuropathySynesthesia

Identifiers

PMID27761598
OpenAlexW2537557035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.