ArticleAnnals of translational medicine2016
Case-crossover design and its implementation in R.
Article in Annals of translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk of Infective Endocarditis Following Invasive Dental Procedures: A Systematic Review and Meta-Analysis.Public health reviews · 2024Pooled it
- Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study.Journal of neurology · 2026Observational
- Climate Change and Preterm Birth: Trends in the Temperate Zone.Deutsches Arzteblatt international · 2025Article
- A case-crossover analysis to quantify the impact of wildfire smoke on hospital respiratory admissions in the Rogue Valley, Oregon.Public health in practice (Oxford, England) · 2024Article
- Trigger factors in patients with a patent foramen ovale-associated stroke: A case-crossover study.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Power outages and pediatric unintentional injury hospitalizations in New York State.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis.The Lancet. Planetary health · 2023Article
- Using Consumer-Wearable Activity Trackers for Risk Prediction of Life-Threatening Heart Arrhythmia in Patients with an Implantable Cardioverter-Defibrillator: An Exploratory Observational Study.Journal of personalized medicine · 2022Article
- Short-term effects of air pollution on respiratory diseases among young children in Wuhan city, China.World journal of pediatrics : WJP · 2022Article
- Article
- Effect Modification by Environmental Quality on the Association between Heatwaves and Mortality in Alabama, United States.International journal of environmental research and public health · 2017Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case-crossover design is a variation of case-control design that it employs persons' history periods as controls. Case-crossover design can be viewed as the hybrid of case-control study and crossover design. Characteristic confounding that is constant within one person can be well controlled with this method. The relative risk and odds ratio, as well as their 95% confidence intervals (CIs), can be estimated using Cochran-Mantel-Haenszel method. R codes for the calculation are provided in the main text. Readers may adapt these codes to their own task. Conditional logistic regression model is another way to estimate odds ratio of the exposure. Furthermore, it allows for incorporation of other time-varying covariates that are not constant within subjects. The model fitting per se is not technically difficult because there is well developed statistical package. However, it is challenging to convert original dataset obtained from case report form to that suitable to be passed to clogit() function. R code for this task is provided and explained in the text.
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Registered trials
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