ArticleFrontiers in pharmacology2016
Hospitalizations Due to Adverse Drug Events in the Elderly-A Retrospective Register Study.
Article in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Hospital admissions due to adverse drug reactions and adverse drug events in older adults: a systematic review.Age and ageing · 2025Pooled it
- Medicines Related Problems (MRPs) Originating in Primary Care Settings in Older Adults - A Systematic Review.Journal of pharmacy practice · 2023Pooled it
- Detection tools for prediction and identification of adverse drug reactions in older patients: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review.European journal of clinical pharmacology · 2021Pooled it
- Potentially inappropriate prescriptions in acutely admitted older patients: a development study to create a clinical decision support tool using a Delphi process.European geriatric medicine · 2026Article
- Computational variant predictors for pharmacogenomics: from evaluation of single alleles to assessment of adverse drug reactions to antidepressants.The pharmacogenomics journal · 2026Article
- Characteristics, preventability, management, and predictors of adverse drug reaction-related hospital admissions: a cross-sectional study in a Thai tertiary care hospital.Journal of pharmaceutical policy and practice · 2026Article
- The Financial and Workforce Impact of Medication Errors in the Finnish Public Healthcare System: A Pilot Study.Health services insights · 2026Article
- Physiologically based pharmacokinetic model to predict drug-drug interactions with the antibody-drug conjugate enfortumab vedotin.Journal of pharmacokinetics and pharmacodynamics · 2024Review
- AEGIS-AcutE Geriatric Intervention Study: pilot study of frontline acute geriatric assessment to improve quality of care in emergency department.Age and ageing · 2024Article
- Prescribing Appropriate Medicines to Older Adults: A Finnish Experience with the Web-Based Meds75+ Database.Drugs & aging · 2024Review
- Exploring the knowledge, perception, and practice of community pharmacists in Saudi Arabia toward pharmacovigilance and adverse drug reaction reporting. A nationwide survey.Scientific reports · 2024Article
- A Real-World Data Derived Pharmacovigilance Assessment on Drug-Induced Nephropathy: Implication on Gaps in Patient Care.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Medication risk checklist for older adults (LOTTA) - development and validation of a self-assessment tool.Annals of medicine · 2023Article
- Effect of Information Intervention on Prescribing Practice for Neuropathic Pain in Older Patients: A Nationwide Register-Based Study.Drugs & aging · 2023Article
- A novel Artificial Intelligence-based tool to assess anticholinergic burden: a survey.Age and ageing · 2022Article
- Prevalence of Polypharmacy and Factors Associated with it Among Saudi Older Adults - Results from the Saudi National Survey for Elderly Health (SNSEH).Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- Prevalence of potentially harmful multidrug interactions on medication lists of elderly ambulatory patients.BMC geriatrics · 2021Article
- Hospital admissions to geriatric ward related to adverse drug events: a cross-sectional study from the Czech Republic.International journal of clinical pharmacy · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse drug events (ADEs) are more likely to affect geriatric patients due to physiological changes occurring with aging. Even though this is an internationally recognized problem, similar research data in Finland is still lacking. The aim of this study was to determine the number of geriatric medication-related hospitalizations in the Finnish patient population and to discover the potential means of recognizing patients particularly at risk of ADEs. The study was conducted retrospectively from the 2014 emergency department patient records in Oulu University Hospital. A total number of 290 admissions were screened for ADEs, adverse drug reactions (ADRs) and drug-drug interactions (DDIs) by a multi-disciplinary research team. Customized Naranjo scale was used as a control method. All admissions were categorized into "probable," "possible," or "doubtful" by both assessment methods. In total, 23.1% of admissions were categorized as "probably" or "possibly" medication-related. Vertigo, falling, and fractures formed the largest group of ADEs. The most common ADEs were related to medicines from N class of the ATC-code system. Age, sex, residence, or specialty did not increase the risk for medication-related admission significantly (min
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