Evidence map›Paper›PMID 27760820›Full record

ReviewJournal of neurophysiology2016

Vestibular implants studied in animal models: clinical and scientific implications.

Richard F Lewis

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07627087 (Vestibular Implant Tested in Patients With Peripheral Vestibular Damage), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07627087 narecruitingnot on this mapstarted 2026, after this paper: background citation

Vestibular Implant Tested in Patients With Peripheral Vestibular Damage: Effects on Spatial Orientation, Navigation, and Neuropsychologic Function

TypeinterventionalSponsorMassachusetts Eye and Ear InfirmaryRan2026 to 2029Enrolled20ConditionsVestibular Dysfunction, Bilateral Vestibular Loss, Vestibular ImplantArmsvestibular implant stimulation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. The Next Challenges of Vestibular Implantation in Humans.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
  4. Review
  5. An Implanted Vestibular Prosthesis Improves Spatial Orientation in Animals with Severe Vestibular Damage.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Regional and Developmental Differences in NaFrontiers in cellular neuroscience · 2018
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Richard F LewisDepartment of Otolaryngology, Harvard Medical School, Boston, Massachusetts; richard_lewis@meei.harvard.edu.

Funding

Vestibular Contributions to Estimated Head Motion and OrientationR01DC013069 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI LEWIS, RICHARD F · 2014 to 2018
$2.7M
NIDCD NIH HHS R01 DC013069
6 · The paper itself

Abstract

Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimulating branches of the vestibular nerve. In this review I consider animal studies performed at our institution over the past 15 years, which have helped elucidate how the brain processes information provided by a vestibular (semicircular canal) implant and how this information could be used to improve the problems experienced by patients with peripheral vestibular damage.

Indexed as

Cochlear ImplantsAnimalsDisease Models, AnimalElectric StimulationHumansPerceptionPostural BalanceVestibular Diseasesataxiaimplantprosthesisvertigovestibular system

Identifiers

PMID27760820
PMCPMC5148793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.