ArticleInternational journal of medical microbiology : IJMM2016
Iron acquisition pathways and colonization of the inflamed intestine by Salmonella enterica serovar Typhimurium.
Article in International journal of medical microbiology : IJMM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- SLC11A2 withholds divalent metals fromProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Protein-centric mechanisms of typhoidalFrontiers in cellular and infection microbiology · 2026Review
- SLC11A2 affects nutritional immunity in the gut epithelium.bioRxiv : the preprint server for biology · 2025Article
- Genomic and Proteomic Analysis of Six Vi01-like Phages Reveals Wide Host Range and Multiple Tail Spike Proteins.Viruses · 2024Article
- Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.Cell host & microbe · 2023Article
- Nutritional immunity: the battle for nutrient metals at the host-pathogen interface.Nature reviews. Microbiology · 2022Review
- Analysis of SixInfection and immunity · 2022Article
- Laser capture microdissection to study Bacillus cereus iron homeostasis gene expression during Galleria mellonella in vivo gut colonization.Virulence · 2021Article
- AraC-type regulators HilC and RtsA are directly controlled by an intestinal fatty acid to regulate Salmonella invasion.Molecular microbiology · 2021Article
- Gene knockout revealed the role of gene feoA in cell growth and division of Lactobacillus delbrueckii subsp. bulgaricus.Archives of microbiology · 2021Article
- Review
- A diffusible signal factor of the intestine dictates Salmonella invasion through its direct control of the virulence activator HilD.PLoS pathogens · 2021Article
- Iron-Uptake Systems of Chicken-AssociatedMicroorganisms · 2020Review
- Xenosiderophore Utilization Promotes Bacteroides thetaiotaomicron Resilience during Colitis.Cell host & microbe · 2020Article
- [Anti-CD206 antibody-conjugated FeNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Transition metals and host-microbe interactions in the inflamed intestine.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2019Review
- Salmonella invasion is controlled through the secondary structure of the hilD transcript.PLoS pathogens · 2019Article
- Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.Nature communications · 2018Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Salmonella enterica serotype Typhimurium is able to expand in the lumen of the inflamed intestine through mechanisms that have not been fully resolved. Here we utilized streptomycin-pretreated mice and dextran sodium sulfate (DSS)-treated mice to investigate how pathways for S. Typhimurium iron acquisition contribute to pathogen expansion in the inflamed intestine. Competitive infection with an iron uptake-proficient S. Typhimurium strain and mutant strains lacking tonB feoB, feoB, tonB or iroN in streptomycin pretreated mice demonstrated that ferric iron uptake requiring IroN and TonB conferred a fitness advantage during growth in the inflamed intestine. However, the fitness advantage conferred by ferrous iron uptake mechanisms was independent of inflammation and was only apparent in models where the normal microbiota composition had been disrupted by antibiotic treatment.
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Registered trials
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