Evidence map›Paper›PMID 27760353›Full record

ArticleBiophysical journal2016

Dynamic Response of the C2 Domain of Protein Kinase Cα to Ca

Krystal A Morales, Yuan Yang, Taylor R Cole, Tatyana I Igumenova

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Genome-Wide Identification of theInternational journal of molecular sciences · 2026
    Article
  2. CaThe journal of physical chemistry. B · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Protein kinase C: perfectly balanced.Critical reviews in biochemistry and molecular biology · 2018
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Krystal A MoralesDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
Yuan YangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
Taylor R ColeDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
Tatyana I IgumenovaDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas. Electronic address: tigumenova@tamu.edu.
Texas A&M University · US

Funding

Structural and Functional Studies of Protein Kinase C RegulationR01GM108998 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI Tatyana I. Igumenova · 2014 to 2026
$3.3M
NIGMS NIH HHS R01 GM108998
6 · The paper itself

Abstract

Ca

Indexed as

Allosteric RegulationApoenzymesC2 DomainsCalciumHydrogen BondingMetalsModels, MolecularProtein BindingProtein Kinase C-alphaApoenzymesCalciumMetalsProtein Kinase C-alpha

Identifiers

PMID27760353
PMCPMC5071625
OpenAlexW2532016108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.