Evidence map›Paper›PMID 27760342›Full record

ArticleImmunity2016

Antiviral CD8

Srinika Ranasinghe, Pedro A Lamothe, Damien Z Soghoian, Samuel W Kazer, Michael B Cole, Alex K Shalek, Nir Yosef, R Brad Jones, Faith Donaghey, Chioma Nwonu and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Immunity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  7. Review
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  10. Review
  11. Article
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  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Conversion of effector CD4Cellular & molecular immunology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 3 countries.

Srinika RanasingheRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA. Electronic address: sranasinghe@mgh.harvard.edu.
Pedro A LamotheRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Damien Z SoghoianRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Samuel W KazerRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 01239, USA; Broad Institute, Cambridge, MA 01239, USA.
Michael B ColeDepartment of Physics, University of California, Berkeley, CA 94720, USA.
Alex K ShalekRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 01239, USA; Broad Institute, Cambridge, MA 01239, USA.
Nir YosefRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Department of Physics, University of California, Berkeley, CA 94720, USA.
R Brad JonesRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; George Washington University, Washington, DC 20052, USA.
Faith DonagheyRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Chioma NwonuRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Priya JaniRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Gina M ClaytonHoward Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Biomedical Research, National Jewish Health, Denver, CO 80206, USA.
Frances CrawfordHoward Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Biomedical Research, National Jewish Health, Denver, CO 80206, USA.
Janice WhiteDepartment of Biomedical Research, National Jewish Health, Denver, CO 80206, USA.
Alana MontoyaDepartment of Biomedical Research, National Jewish Health, Denver, CO 80206, USA.
Karen PowerRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Todd M AllenRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA.
Hendrik StreeckInstitute for HIV Research, University Hospital, University Duisburg-Essen, Essen 45147, Germany; U.S. Military HIV Research Program, Henry M. Jackson Foundation, Rockville, MD 20910, USA.
Daniel E KaufmannRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Centre de Recherche du Centre hospitalier de l'Université de Montréal, Montreal, QC H2X 3J4, Canada.
Louis J PickerVaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
John W KapplerHoward Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Biomedical Research, National Jewish Health, Denver, CO 80206, USA.
Bruce D WalkerRagon Institute of MGH, MIT and Harvard, Cambridge, MA 01239, USA; Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 01239, USA; Broad Institute, Cambridge, MA 01239, USA. Electronic address: bwalker@mgh.harvard.edu.
Ragon Institute of MGH, MIT and Harvard · USHoward Hughes Medical Institute · USMassachusetts Institute of Technology · USNational Jewish Health · USUniversity of Colorado Denver · USGeorge Washington University · USHenry M. Jackson Foundation · USOregon National Primate Research Center · USUniversity of California, Berkeley · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Vaccine Adjuvant/ Delivery Systems CoreP01AI104715 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ALLEN, TODD M · 2013 to 2017
$12.3M
"Bottom - Up" Profiling of Interacting Cellular SystemsDP2GM119419 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SHALEK, ALEX K · 2015 to 2015
$2.3M
An integrated multiplexed genomic assay for low input clinical samples1U24AI118672 · NIAID · BROAD INSTITUTE, INC. · PI SHALEK, ALEX K · 2015 to 2019
$2.0M
Molecular Mechanisms of MHCII Recognition by CD8 T Cells in HIV Non-Progressor PatientsR21AI125085 · NIAID · NATIONAL JEWISH HEALTH · PI KAPPLER, JOHN W · 2016 to 2017
$436k
Howard Hughes Medical InstituteNIAID NIH HHS P01 AI104715NIAID NIH HHS P30 AI060354NIAID NIH HHS R21 AI125085NIAID NIH HHS U24 AI118672NIGMS NIH HHS DP2 GM119419
6 · The paper itself

Abstract

CD8

Indexed as

Antiviral AgentsCD8-Positive T-LymphocytesHistocompatibility Antigens Class IIHIV InfectionsHLA AntigensHumansReceptors, Antigen, T-Cell, alpha-betaAntiviral AgentsHistocompatibility Antigens Class IIHLA AntigensReceptors, Antigen, T-Cell, alpha-betaCD8(+) T cellsHIVHLAMHC class IITCRvaccines

Identifiers

PMID27760342
PMCPMC5077698
OpenAlexW2537525060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.