ArticleCell reports2016
Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
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Article in Cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
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- Fluorescence tracking CD8 T cells from tumor-draining lymph nodes to irradiated tumors and their activation in the tumor environment.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- TLR7-mediated inflammation drives PD-L1 upregulation and T cell exhaustion during influenza A virus infection.iScience · 2026Article
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- Harnessing SARS-CoV-2 immunity to promote antitumor responses through intratumoral vaccination and adoptive transfer.Frontiers in immunology · 2026Article
- Human Endogenous Retroviruses and Diseases.MedComm · 2025Review
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- What do atomic bomb survivors teach us about therapy-free remission in people with chronic myeloid leukaemia?Leukemia · 2024Article
- Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control.PLoS pathogens · 2024Article
- COVID-19 Associated Acute Viral Myocarditis and Thyroid Gland Follicular Neoplasm in a Hemodialysis Patient.Oman medical journal · 2023Article
- Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection.Translational research : the journal of laboratory and clinical medicine · 2022Review
- Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment.Frontiers in immunology · 2021Review
- Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Aurora A controls CD8Scientific reports · 2019Article
- Immunobiochemical Reconstruction of Influenza Lung Infection-Melanoma Skin Cancer Interactions.Frontiers in immunology · 2019Article
- Nanoscale Peptide Self-assemblies Boost BCG-primed Cellular Immunity Against Mycobacterium tuberculosis.Scientific reports · 2018Article
- Article
- Viruses, bacteria, and parasites - oh my! a resurgence of interest in microbial-based therapy for cancer.Journal for immunotherapy of cancer · 2018Article
- Infection: a Cause of and Cure for Cancer.Current pharmacology reports · 2017Review
- Tumour immunology: The consequences of concomitant challenges.Nature reviews. Cancer · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 8 institutions in 2 countries.
Frederick J KohlhappSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
Erica J HuelsmannDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Andrew T LacekDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Jason M SchenkelDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Jevgenijs LusciksDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
Joseph R BroucekDepartment of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Josef W GoldufskyDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Tasha HughesDepartment of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Janet P ZayasDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Hubert DolubiznoDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Ryan T SowellDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Regina KühnerDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Sarah BurdUniversity of Oxford, Oxford OX1 2JD, UK.
John C KubasiakDepartment of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Arman NabatiyanDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
Sh'Rae MarshallSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Praveen K BommareddySection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Shengguo LiSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Jenna H NewmanSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Claude E MonkenSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
Sasha H ShafikhaniDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
Amanda L MarzoDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
Jose A Guevara-PatinoDepartment of Surgery, Immunology Institute, Cardinal Bernardin Cancer Center, Loyola University Chicago, Maywood, IL 60153, USA.
Ahmed LasfarSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Paul G ThomasDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Edmund C LattimeSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
Howard L KaufmanSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
Andrew ZlozaSection of Surgical Oncology, Division of Surgical Oncology Research, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA. Electronic address: andrew.zloza@rutgers.edu.
Rush University Medical Center · USRutgers Cancer Institute of New JerseyRutgers, The State University of New Jersey · USJohnson University · USLoyola University Chicago · USSt. Jude Children's Research Hospital · USUniversity of Minnesota · USUniversity of Oxford · GB
Funding
TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5MIMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1MUMDNJ TRAINING GRANT IN BIOTECHNOLOGYT32GM008339 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI YARMUSH, MARTIN L · 1989 to 2019
$6.1MMechanisms to diversify repertoire and modify T cell activity after infectionR01AI107625 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI THOMAS, PAUL G. · 2013 to 2017
$2.3MNCI NIH HHS P30 CA072720NHLBI NIH HHS T32 HL007974NIAID NIH HHS R01 AI107625NIGMS NIH HHS T32 GM008339
Abstract
In light of increased cancer prevalence and cancer-specific deaths in patients with infections, we investigated whether infections alter anti-tumor immune responses. We report that acute influenza infection of the lung promotes distal melanoma growth in the dermis and leads to accelerated cancer-specific host death. Furthermore, we show that during influenza infection, anti-melanoma CD8
Indexed as
OncogenesAcute DiseaseAnimalsCD8-Positive T-LymphocytesCell ProliferationLungMelanomaMice, Inbred BALB CMice, Inbred C57BLOrthomyxoviridae InfectionsProgrammed Cell Death 1 ReceptorProgrammed Cell Death 1 Receptorbreast cancercancerCD8(+) T cellsconcomitantinfectioninfluenzamelanomamousePD-1viral
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.