Evidence map›Paper›PMID 27759160›Full record

ReviewBritish journal of pharmacology2016

Snapshot: implications for melatonin in endoplasmic reticulum homeostasis.

Wei Hu, Zhiqiang Ma, Shouyin Di, Shuai Jiang, Yue Li, Chongxi Fan, Yang Yang, Dongjin Wang

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The oral microbiome in young women at different stages of periodontitis:Frontiers in cellular and infection microbiology · 2022
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Promising Antineoplastic Actions of Melatonin.Frontiers in pharmacology · 2018
    Review
  12. Article
  13. Article
  14. Melatonin and mitochondrial function during ischemia/reperfusion injury.Cellular and molecular life sciences : CMLS · 2017
    Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wei HuDepartment of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Zhiqiang MaDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
Shouyin DiDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
Shuai JiangDepartment of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China.
Yue LiDepartment of Biomedical Engineering, The Fourth Military Medical University, Xi'an, China.
Chongxi FanDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
Yang YangDepartment of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Dongjin WangDepartment of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Air Force Medical University · CNNanjing Drum Tower Hospital · CNTang Du Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) is an important intracellular membranous organelle. Previous studies have demonstrated that the ER is responsible for protein folding and trafficking, lipid synthesis and the maintenance of calcium homeostasis. Interestingly, the morphology and structure of the ER were recently found to be important. Melatonin is a hormone that anticipates the daily onset of darkness in mammals, and it is well known that melatonin acts as an antioxidant by scavenging free radicals and increasing the activity of antioxidant enzymes in the body. Notably, the existing evidence demonstrates that melatonin is involved in ER homeostasis, particularly in the morphology of the ER, indicating a potential protective role of melatonin. This review discusses the existing knowledge regarding the implications for the involvement of melatonin in ER homeostasis.

Indexed as

HomeostasisEndoplasmic ReticulumHumansMelatoninMelatonin

Identifiers

PMID27759160
PMCPMC5120159
OpenAlexW2532761782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.