Evidence map›Paper›PMID 27759105›Full record

ArticleScientific reports2016

Nondestructive, real-time determination and visualization of cellulose, hemicellulose and lignin by luminescent oligothiophenes.

Ferdinand X Choong, Marcus Bäck, Svava E Steiner, Keira Melican, K Peter R Nilsson, Ulrica Edlund, Agneta Richter-Dahlfors

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Fluorescent optotracers for bacterial and biofilm detection and diagnostics.Science and technology of advanced materials · 2023
    Review
  3. Structural Properties Dictating Selective Optotracer Detection of Staphylococcus aureus.Chembiochem : a European journal of chemical biology · 2022
    Article
  4. Review
  5. Optotracing for live selective fluorescence-based detection ofFrontiers in cellular and infection microbiology · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ferdinand X ChoongSwedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institutet, Stockholm, SE-171 77, Sweden.
Marcus BäckDivision of Chemistry, Department of Physics, Chemistry and Biology, Linköping University, Linköping, SE-581 83, Sweden.
Svava E SteinerSwedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institutet, Stockholm, SE-171 77, Sweden.
Keira MelicanSwedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institutet, Stockholm, SE-171 77, Sweden.
K Peter R NilssonDivision of Chemistry, Department of Physics, Chemistry and Biology, Linköping University, Linköping, SE-581 83, Sweden.
Ulrica EdlundFiber and Polymer Technology, KTH Royal Institute of Technology, Stockholm, SE-100 44, Sweden.
Agneta Richter-DahlforsSwedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institutet, Stockholm, SE-171 77, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enabling technologies for efficient use of the bio-based feedstock are crucial to the replacement of oil-based products. We investigated the feasibility of luminescent conjugated oligothiophenes (LCOs) for non-destructive, rapid detection and quality assessment of lignocellulosic components in complex biomass matrices. A cationic pentameric oligothiophene denoted p-HTEA (pentamer hydrogen thiophene ethyl amine) showed unique binding affinities to cellulose, lignin, hemicelluloses, and cellulose nanofibrils in crystal, liquid and paper form. We exploited this finding using spectrofluorometric methods and fluorescence confocal laser scanning microscopy, for sensitive, simultaneous determination of the structural and compositional complexities of native lignocellulosic biomass. With exceptional photostability, p-HTEA is also demonstrated as a dynamic sensor for real-time monitoring of enzymatic cellulose degradation in cellulolysis. These results demonstrate the use of p-HTEA as a non-destructive tool for the determination of cellulose, hemicellulose and lignin in complex biomass matrices, thereby aiding in the optimization of biomass-converting technologies.

Indexed as

BiomassBiosensing TechniquesCelluloseComplex MixturesFeasibility StudiesLigninLuminescent MeasurementsNanofibersPolysaccharidesThiophenesCelluloseComplex MixtureshemicelluloseLigninPolysaccharidesThiophenes

Identifiers

PMID27759105
PMCPMC5069672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.