Evidence map›Paper›PMID 27758117›Full record

ArticleAIDS research and human retroviruses2017

A Proposed Framework for the Implementation of Early Infant Diagnosis Point-of-Care.

Karidia Diallo, Surbhi Modi, Mackenzie Hurlston, R Suzanne Beard, John N Nkengasong

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karidia Diallo1 International Laboratory Branch, Centers for Disease Control and Prevention , Atlanta, Georgia .
Surbhi Modi2 Maternal and Child Health Branch, Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention , Atlanta, Georgia .
Mackenzie Hurlston1 International Laboratory Branch, Centers for Disease Control and Prevention , Atlanta, Georgia .
R Suzanne Beard1 International Laboratory Branch, Centers for Disease Control and Prevention , Atlanta, Georgia .
John N Nkengasong1 International Laboratory Branch, Centers for Disease Control and Prevention , Atlanta, Georgia .

Funding

PEPFAR
6 · The paper itself

Abstract

Early diagnosis of HIV infection in infants and children remains a challenge in resource-limited settings, with approximately half of all HIV-exposed infants receiving virological testing for HIV by the recommended age of 2 months in 2015. To reduce morbidity and mortality among HIV-infected children and close the treatment gap for HIV-infected children, there is an urgent need to evaluate existing programmatic and laboratory practices for early infant diagnosis and introduce strategies to improve identification of HIV-exposed infants and ensure access to systematic, early HIV testing, with early linkage to treatment for HIV-infected infants. This article describes progress made in follow-up of HIV-exposed infants since 2006, including remaining unmet laboratory and programmatic needs, and recommends strategies for improvement, especially those related to the implementation of point-of-care technology for early infant diagnosis.

Indexed as

Point-of-Care SystemsEarly DiagnosisHIV InfectionsHumansInfantMass Screeningearly infant diagnosisHIVnear point-of-carepoint-of-care

Identifiers

PMID27758117
PMCPMC5333568

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.