Evidence map›Paper›PMID 27757839›Full record

ArticleInternational urology and nephrology2017

Modification of the 2012 CKD-EPI equations for the elderly Chinese.

Fen Li, Xiaohua Pei, Xiaoshuang Ye, Xun Liu, Dan Song, Xiaoxuan Zhang, Bei Zhu, Lu Wei, Jin Zhu, Weihong Zhao

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Article in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fen LiDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Xiaohua PeiDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Xiaoshuang YeDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Xun LiuDepartmentof Nephrology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
Dan SongDepartment of Nephrology, The Affiliated Wuxi No.2 Hospital of Nanjing Medical University, Wuxi, Jiangsu, People's Republic of China.
Xiaoxuan ZhangDepartment of Nephrology, The Fourth Hospital of Jilin University, Changchun, Jilin, People's Republic of China.
Bei ZhuDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Lu WeiDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Jin ZhuInstitute of Pattern Recognition and Machine Intelligence, School of Computer Science, Nanjing University of Science and Technology, Nanjing, Jiangsu, People's Republic of China.
Weihong ZhaoDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China. zhaoweihongny@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur previous studies demonstrated that 2012 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations were inaccurate enough for estimating glomerular filtration rate in elderly Chinese. Thus, this study was constructed to modify these equations.

methodsA total of 839 subjects (aged ≥60 years) from four hospitals in China between October 2009 and December 2014 were included. A random sample of 674 (80.3 %) subjects was used as a training sample set, and the remaining 165 (19.7 %) subjects as the verification set. The equations were modified using the hill-climbing algorithm.

resultsCompared with the original CKD-EPI equations, the accuracy assessment indexes (bias, precision, accuracy and misclassification) were obviously improved after modification. Bland-Altman analysis also demonstrated that this modification attempt gained success to some extent.

conclusionsThe modified 2012 CKD-EPI equations could be more accurate than the original equations for elderly Chinese individuals.

Indexed as

AlgorithmsGlomerular Filtration RateAgedChinaCreatinineCystatin CFemaleHumansMaleMiddle AgedRadiopharmaceuticalsRenal Insufficiency, ChronicReproducibility of ResultsTechnetium Tc 99m PentetateCreatinineCystatin CRadiopharmaceuticalsTechnetium Tc 99m PentetateChronic kidney diseaseElderlyEstimation equationsGlomerular filtration rate

Identifiers

PMID27757839

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.