SynthesisJournal of clinical monitoring and computing2017
Cerebral hemodynamics in sepsis assessed by transcranial Doppler: a systematic review and meta-analysis.
Synthesis in Journal of clinical monitoring and computing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Profiling cerebral hemodynamics in sepsis and septic shock patients with transcranial doppler: a systematic review and meta-analysis.Journal of clinical monitoring and computing · 2026Pooled it
- Monitoring of Cerebral Blood Flow Autoregulation after Cardiac Arrest.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review.Frontiers in neurology · 2021Pooled it
- ARISE framework: a temporal, multi-organ view of perfusion in sepsis.Internal and emergency medicine · 2026Review
- The role of transcranial Doppler in predicting the incidence and prognosis of sepsis-associated encephalopathy.Intensive care medicine experimental · 2025Article
- Bosutinib mitigates inflammation in experimental sepsis.European journal of clinical investigation · 2025Article
- Alterations in Regional Brain Microcirculation in Patients with Sepsis: A Prospective Study Using Contrast-Enhanced Brain Ultrasound.Neurocritical care · 2025Article
- Observational Examination of Cerebral Perfusion Changes in Patients Diagnosed with Sepsis Using Transcranial Doppler Ultrasonography.Tanaffos · 2025Article
- Brain Ultrasonography in Critically Ill Septic Patients: A Scoping Review.Journal of clinical medicine · 2024Article
- The Usefulness of Carotid Artery Doppler Measurement as a Predictor of Early Death in Sepsis Patients Admitted to the Emergency Department.Journal of clinical medicine · 2024Article
- Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning.World journal of critical care medicine · 2024Review
- Improved Transcranial Doppler Waveform Analysis for Intracranial Hypertension Assessment in Patients with Traumatic Brain Injury.Neurocritical care · 2024Article
- Estimated Cerebral Perfusion Pressure and Intracranial Pressure in Septic Patients.Neurocritical care · 2024Article
- Cerebral hemodynamics and optic nerve sheath diameter acquired via neurosonology in critical patients with severe coronavirus disease: experience of a national referral hospital in Peru.Frontiers in neurology · 2024Article
- The importance of monitoring cerebral oxygenation in non brain injured patients.Journal of clinical monitoring and computing · 2023Review
- Optimizing the prediction of sepsis-associated encephalopathy with cerebral circulation time utilizing a nomogram: a pilot study in the intensive care unit.Frontiers in neurology · 2023Article
- POCUS, how can we include the brain? An overview.Journal of anesthesia, analgesia and critical care · 2022Review
- Changes in Arterial Carbon Dioxide Partial Pressure Do Not Affect Cerebral Autoregulation in Septic Patients.Neurocritical care · 2022Article
- Automated Pupillometry as an Assessment Tool for Intracranial Hemodynamics in Septic Patients.Cells · 2022Observational
- The Importance of Neuromonitoring in Non Brain Injured Patients.Critical care (London, England) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral microcirculation is gradually compromised during sepsis, with significant reductions in the function of capillaries and blood perfusion in small vessels. Transcranial Doppler ultrasound (TCD) has been used to assess cerebral circulation in a typical clinical setting. This study was to systematically review TCD studies, assess their methodological quality, and identify trends that can be associated with the temporal evolution of sepsis and its clinical outcome. A meta-analysis of systematic reviews was conducted according to the PRISMA statement. Articles were searched from 1982 until the conclusion of this review in December 2015. Twelve prospective and observational studies were selected. Evaluations of cerebral blood flow, cerebral autoregulation, and carbon dioxide (CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.