ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2016
3-T intraoperative MRI (iMRI) for pediatric epilepsy surgery.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 18 citations in OpenAlex.
- Intraoperative magnetic resonance imaging during surgical resection for drug resistant epilepsy eliminates the incidence of inadvertent incomplete resection of the epileptogenic zone and early surgical failure.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- No association between histopathology and neurophysiology in surgical specimens from pediatric focal epilepsy patients.Epilepsia · 2025Article
- Single-cell Raman spectroscopy detects pediatric focal cortical dysplasia.Biophotonics discovery · 2025Article
- Evaluating the use of intraoperative magnetic resonance imaging in paediatric brain tumour resection surgeries: a literature review.Journal of medical radiation sciences · 2023Review
- Changing concepts in presurgical assessment for epilepsy surgery.Nature reviews. Neurology · 2019Review
- The impact of intraoperative magnetic resonance in routine pediatric neurosurgical practice-a 6-year appraisal.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
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8 authors at 1 institution in 1 country.
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Abstract
purposeThree-tesla intraoperative MRI (iMRI) is a promising tool that could help confirm complete resections and disconnections in pediatric epilepsy surgery, leading to improved outcomes. However, a large proportion of epileptogenic pathologies in children are poorly defined on imaging, which brings into question the utility of iMRI for these cases. Our aim was to compare postoperative seizure outcomes between iMRI- and non-iMRI-based epilepsy surgeries.
methodsWe performed a comparative retrospective analysis of non-iMRI- versus iMRI-based epilepsy surgeries with 2-year follow-up. Patients were stratified into well-defined cases (WDCs), poorly defined cases (PDCs), and diffuse hemispheric cases (DHCs). Primary outcomes were rates of complete seizure freedom and surgical complications. Secondary outcomes included good (Engel class I/II) seizure outcome, extent of resection/disconnection, and operative duration. Regression models were used to adjust for confounding.
resultsThirty-nine iMRI-based and 39 non-iMRI-based surgeries were included. The distributions of age, sex, and lesion class in each era were similar, but the distributions of individual pathologies varied. Seizure freedom and complication rates at 2-year follow-up were not different between the groups, but Engel class I/II outcome was more common in the iMRI group. Extent of resection/disconnection and length of surgery were similar in both groups. PDCs had the worst outcomes, which were unchanged by the use of iMRI.
conclusionThree-tesla iMRI-based epilepsy surgery may have the potential to improve patient outcomes. However, we conclude that iMRI, in its current state of use at our institute, does not improve outcomes for children undergoing epilepsy surgery. Given that its use appears safe, further research on this technology is warranted, particularly for the most challenging PDCs.
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