Evidence map›Paper›PMID 27757502›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2016

Simultaneous integrated protection : A new concept for high-precision radiation therapy.

Thomas B Brunner, Ursula Nestle, Sonja Adebahr, Eleni Gkika, Rolf Wiehle, Dimos Baltas, Anca-Ligia Grosu

Abstract readCase Reports
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  18. Treatment plan quality during online adaptive re-planning.Radiation oncology (London, England) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas B BrunnerDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland. thomas.brunner@uniklinik-freiburg.de.
Ursula NestleDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.
Sonja AdebahrDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.
Eleni GkikaDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.
Rolf WiehleDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.
Dimos BaltasDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.
Anca-Ligia GrosuDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStereotactic radiotherapy near serial organs at risk (OAR) requires special caution. A novel intensity-modulated radiotherapy (IMRT) prescription concept termed simultaneous integrated protection (SIP) for quantifiable and comparable dose prescription to targets very close to OAR is described. MATERIALS AND

methodsAn intersection volume of a planning risk volume (PRV) with the total planning target volume (PTV) defined the protection volume (PTV

resultsSIP was applied in 6 patients with OAR being large airways (n = 2) or bowel (n = 4) in 3, 5, 8, and 12 fractions in 1, 3, 1, and 1 patients, respectively. PTVs were 14.5-84.9 ml and PTV

conclusionSIP results in a median dose of ≥100 % to PTV, to achieve high local control and low toxicity. Longer follow-up is required to verify results and a prospective clinical trial is currently testing this new approach in chest and abdomen stereotactic body radiotherapy.

Indexed as

Dose-Response Relationship, RadiationHumansNeoplasmsOrgans at RiskOrgan Sparing TreatmentsRadiation Dose HypofractionationRadiation InjuriesRadiation ProtectionRadiosurgeryRadiotherapy Planning, Computer-AssistedReproducibility of ResultsSensitivity and SpecificityTreatment OutcomeEfficacyIntensity-modulated radiotherapyOrgans at riskStereotactic body radiation therapyToxicity

Identifiers

PMID27757502
PMCPMC5122615

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.