Evidence map›Paper›PMID 27757383›Full record

ArticleJournal of exercise nutrition & biochemistry2016

Effects of voluntary exercise on apoptosis and cortisol after chronic restraint stress in mice.

Hyobin Seo, Chun-Hyung Park, Seokrip Choi, Woocheol Kim, Byung-Duk Jeon, Seungpil Ryu

Abstract read
In one paragraph

Article in Journal of exercise nutrition & biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Article
  7. Individualized Running Wheel System with a Dynamically Adjustable Exercise Area and Speed for Rats Following Ischemic Stroke.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyobin SeoDepartment of Leisure Sports, Kyungpook National University, Sangju Republic of Korea.
Chun-Hyung ParkDepartment of Leisure Sports, Kyungpook National University, Sangju Republic of Korea.
Seokrip ChoiDepartment of Sports Rehabilitation, Daegu Health College, Daegu Republic of Korea.
Woocheol KimDepartment of Sports Rehabilitation, Daegu Health College, Daegu Republic of Korea.
Byung-Duk JeonDepartment of Physical Education Leisure, Suseong College, Daegu Republic of Korea.
Seungpil RyuDepartment of Leisure Sports, Kyungpook National University, Sangju Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether voluntary exercise (wheel running) has the potential of relieving stress.

methodsIn this study, restraint stress with or without voluntary wheel running was performed for mice housed in individual cages. A total of 21 ICR male mice were assigned into control (CON), restraint stress with voluntary exercise (RSVE), or restraint stress (RS) without voluntary exercise groups (n = 7 each).

resultsNo significant difference in body weight increase was found among the three groups, although CON and RS groups had a tendency of having smaller body weight increase compared to the RSVE group. No significant difference in the expression level of liver heat shock protein 70, Bcl-2, or p53 was found among the three groups. However, caspase-3 protein level in RS group was significantly higher than that in the other two groups. Blood cortisol concentration in RS was higher (p < 0.05) than that in RSVE or CON group. It was the lowest (p < 0.05) in the RSVE group.

conclusionOur findings suggest that apoptosis caused by chronic restraint stress might be suppressed by voluntary exercise in mice.

Indexed as

ApoptosisCortisolMiceRestraint stressVoluntary exercise

Identifiers

PMID27757383
PMCPMC5067423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.