Evidence map›Paper›PMID 27757308›Full record

ArticleOncoimmunology

Chemo-immunotherapy mediates durable cure of orthotopic K

Vanaja Konduri, Dali Li, Matthew M Halpert, Dan Liang, Zhengdong Liang, Yunyu Chen, William E Fisher, Silke Paust, Jonathan M Levitt, Qizhi Cathy Yao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Article
  10. Article
  11. Review
  12. MHC class I and II peptide homology regulates the cellular immune response.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  13. CD8Frontiers in immunology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. AIMp1 Potentiates TFrontiers in immunology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Vanaja KonduriDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.
Dali LiMichael E. Debakey Department of Surgery, Baylor College of Medicine , Houston, TX, USA.
Matthew M HalpertDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.
Dan LiangDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.
Zhengdong LiangMichael E. Debakey Department of Surgery, Baylor College of Medicine , Houston, TX, USA.
Yunyu ChenDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.
William E FisherMichael E. Debakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA; Elkins Pancreas Center, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Silke PaustDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Center for Human Immunobiology, Baylor College of Medicine, Houston, TX, USA.
Jonathan M LevittDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
Qizhi Cathy YaoDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Michael E. Debakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA; Elkins Pancreas Center, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Center for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey VA Medical Center, Houston, TX, USA.
William K DeckerDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USChildren's Cancer Center · USMichael E. DeBakey VA Medical Center · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 1994 to 2015
$21.7M
A novel miR-198 replacement therapy for pancreatic cancerR01CA183984 · NCI · BAYLOR COLLEGE OF MEDICINE · PI YAO, QIZHI C. · 2015 to 2019
$2.4M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA183984NCRR NIH HHS S10 RR024574NIAID NIH HHS P30 AI036211
6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States, exhibiting a five-year overall survival (OS) of only 7% despite aggressive standard of care. Recent advances in immunotherapy suggest potential application of immune-based treatment approaches to PDAC. To explore this concept further, we treated orthotopically established K-ras

Indexed as

Adjuvant therapyPDACtumor immunologyvaccination

Identifiers

PMID27757308
PMCPMC5048769
OpenAlexW2498377998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.