ReviewDialogues in clinical neuroscience2016
Individual variation in functional brain connectivity: implications for personalized approaches to psychiatric disease.
Review in Dialogues in clinical neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- Article
- Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome.Biological psychiatry global open science · 2026Article
- Article
- Neural manifold connectomics reveals multiregime functional connectivity.bioRxiv : the preprint server for biology · 2026Article
- Age-stratified individual-specific subspace of autism spectrum disorder based on common orthogonal basis extraction algorithm improves the accuracy of clinical symptoms prediction.BMC psychiatry · 2026Article
- Disentangling individual heterogeneity reveals robust network and molecular signatures of major depressive disorder with suicidal ideation.Translational psychiatry · 2026Article
- VarCoNet: A Variability-Aware Self-Supervised Framework for Functional Connectome Extraction From Resting-State fMRI.Human brain mapping · 2026Article
- Sex Classification Based on the Functional Connectivity Patterns of the Language Network: A Resting State fMRI Study.Human brain mapping · 2026Article
- Higher-order statistics for constructing centered edge functional connectivity.Network neuroscience (Cambridge, Mass.) · 2026Article
- Voxel-Wise or Region-Wise Nuisance Regression for Functional Connectivity Analyses: Does It Matter?Human brain mapping · 2025Article
- Precision functional mapping reveals less inter-individual variability in the child vs. adult human brain.bioRxiv : the preprint server for biology · 2025Article
- The Beholder's Share: Bridging art and neuroscience to study individual differences in subjective experience.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Topological signatures of brain dynamics: persistent homology reveals individuality and brain-behavior links.Frontiers in human neuroscience · 2025Article
- Comparing and scaling fMRI features for brain-behavior prediction.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Individual connectivity-based parcellations reflect functional properties of human auditory cortex.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Functional connectivity heterogeneity and consequences for clinical and cognitive prediction: Stage 2 registered report.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Brain-Cognition Fingerprinting via Graph-GCCA with Contrastive Learning.Machine learning in clinical neuroimaging : 7th international workshop, MLCN 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 10, 2024, proceedings. MLCN (Workshop) (7th : 2024 : Marrakesh, Morocco) · 2025Article
- Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Consecutive-Contrastive Spherical U-Net: Enhancing Reliability of Individualized Functional Brain Parcellation for Short-Duration fMRI Scans.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024Article
- Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale.PLoS biology · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional brain connectivity measured with functional magnetic resonance imaging (fMRI) is a popular technique for investigating neural organization in both healthy subjects and patients with mental illness. Despite a rapidly growing body of literature, however, functional connectivity research has yet to deliver biomarkers that can aid psychiatric diagnosis or prognosis at the single-subject level. One impediment to developing such practical tools has been uncertainty regarding the ratio of intra- to interindividual variability in functional connectivity; in other words, how much variance is state- versus trait-related. Here, we review recent evidence that functional connectivity profiles are both reliable within subjects and unique across subjects, and that features of these profiles relate to behavioral phenotypes. Together, these results suggest the potential to discover reliable correlates of present and future illness and/or response to treatment in the strength of an individual's functional brain connections. Ultimately, this work could help develop personalized approaches to psychiatric illness.
Indexed as
Identifiers
27757062PMC5067145What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.