Evidence map›Paper›PMID 27757056›Full record

ArticleNature and science of sleep2016

Epiglottis cross-sectional area and oropharyngeal airway length in male and female obstructive sleep apnea patients.

Melinda A Ma, Rajesh Kumar, Paul M Macey, Frisca L Yan-Go, Ronald M Harper

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature and science of sleep, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Transoral glossoepiglottopexy in the treatment of adult obstructive sleep apnoea: a surgical approach.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Melinda A MaDepartment of Neurobiology.
Rajesh KumarDepartment of Anesthesiology; Department of Radiological Sciences, David Geffen School of Medicine; Brain Research Institute.
Paul M MaceyBrain Research Institute; UCLA School of Nursing.
Frisca L Yan-GoDepartment of Neurology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Ronald M HarperDepartment of Neurobiology; Brain Research Institute.
Institute of Neurobiology · BGUniversity of California, Los Angeles · US

Funding

Blood-Brain Barrier Deficit and Brain Injury in Obstructive Sleep ApneaR01NR015038 · NINR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUMAR, RAJESH · 2015 to 2018
$2.0M
Brain Axonal Injury in Obstructive Sleep ApneaR01HL113251 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUMAR, RAJESH · 2012 to 2015
$1.4M
NHLBI NIH HHS R01 HL113251NINR NIH HHS R01 NR015038
6 · The paper itself

Abstract

introductionObstructive sleep apnea (OSA) is a male-predominant condition, characterized by repeated upper-airway collapse with continued diaphragmatic efforts during sleep, and is accompanied by severe physiological consequences. Multiple morphological aspects, including epiglottis cross-sectional area (CSA) and oropharyngeal airway length (OPAL), can contribute to airway collapsibility in the condition. This study focused on the effects of OSA severity, sex, and race on OPA dimensions. MATERIALS AND

methodsTwo high-resolution

resultsSignificantly reduced epiglottis CSA appeared only in severe OSA vs controls (

conclusionSex-based reductions in epiglottis CSA and increased OPAL in OSA subjects may enhance airway-collapse vulnerability, more so with greater disease severity, and partially underlie male vs female susceptibility to the sleep disorder.

Indexed as

apnea–hypopnea indexgendermagnetic resonance imagingraceupper-airway length

Identifiers

PMID27757056
PMCPMC5055050
OpenAlexW2528779053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.