Evidence map›Paper›PMID 27756619›Full record

ArticleAnaerobe2016

Effect of smokeless tobacco products on human oral bacteria growth and viability.

Min Liu, Jinshan Jin, Hongmiao Pan, Jinhui Feng, Carl E Cerniglia, Maocheng Yang, Huizhong Chen

Open access · greenAbstract read
In one paragraph

Article in Anaerobe, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Min LiuDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States; Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
Jinshan JinDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States.
Hongmiao PanDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States; Key Laboratory of Marine Ecology & Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.
Jinhui FengDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States; National Engineering Laboratory for Industrial Enzymes, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Carl E CernigliaDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States.
Maocheng YangOffice of Science, Center for Tobacco Products, U.S. Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, United States. Electronic address: Maocheng.Yang@fda.hhs.gov.
Huizhong ChenDivision of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, United States. Electronic address: Huizhong.Chen@fda.hhs.gov.
National Center for Toxicological Research · USChinese Academy of Sciences · CNUnited States Food and Drug Administration · US

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

To evaluate the toxicity of smokeless tobacco products (STPs) on oral bacteria, seven smokeless tobacco aqueous extracts (STAEs) from major brands of STPs and three tobacco-specific N-nitrosamines (TSNAs) were used in a growth and viability test against 38 oral bacterial species or subspecies. All seven STAEs showed concentration-dependent effects on the growth and viability of tested oral bacteria under anaerobic culture conditions, although there were strain-to-strain variations. In the presence of 1 mg/ml STAEs, the growth of 4 strains decreased over 0.32-2.14 log

Indexed as

Complex MixturesCulture MediaEubacteriumHumansHydrogen-Ion ConcentrationMicrobial ViabilityMicrobiotaMouthNitrosaminesPeptostreptococcusSpecies SpecificityStreptococcus anginosusStreptococcus constellatusTobacco, SmokelessVeillonellaComplex MixturesCulture MediaNitrosaminesCell viabilityOral bacteriaSmokeless tobaccoTobacco-specific N-nitrosaminesToxicology

Identifiers

PMID27756619
PMCPMC5693344
OpenAlexW2537247332

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.