Evidence map›Paper›PMID 27756514›Full record

Trial reportSchizophrenia research2017

Confirmatory factor analysis of the quality of life scale and new proposed factor structure for the quality of life scale-revised.

Kim T Mueser, Min Kim, Jean Addington, Susan R McGurk, Sarah I Pratt, Donald E Addington

Abstract readMulticenter StudyRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Schizophrenia research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Focusing on recovery goals improves motivation in first-episode psychosis.Social psychiatry and psychiatric epidemiology · 2020
    Article
  9. Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kim T MueserCenter for Psychiatric Rehabilitation, Departments of Occupational Therapy, Psychology, and Psychiatry, Boston University, Boston, MA, USA. Electronic address: mueser@bu.edu.
Min KimCenter for Psychiatric Rehabilitation, Boston University, Boston, MA, USA.
Jean AddingtonDepartment of Psychiatry, University of Calgary, Calgary, Canada.
Susan R McGurkCenter for Psychiatric Rehabilitation, Departments of Occupational Therapy, Psychology, and Psychiatry, Boston University, Boston, MA, USA.
Sarah I PrattDepartment of Psychiatry, the Geisel School of Medicine at Dartmouth, Hanover, NH, USA; the Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Hanover, NH, USA.
Donald E AddingtonDepartment of Psychiatry, University of Calgary, Calgary, Canada.

Funding

Evaluation of BDNF as a Mediator of the Effects of Cognitive Remediation in persons with SMIR01MH077210 · NIMH · DARTMOUTH COLLEGE · PI MCGURK, SUSAN R. · 2006 to 2016
$4.1M
Individually Based Psychosocial Rehabilitation for Older People with SMIK23MH080021 · NIMH · DARTMOUTH COLLEGE · PI PRATT, SARAH ILANA · 2008 to 2012
$856k
NIMH NIH HHS K23 MH080021NIMH NIH HHS R01 MH077210
6 · The paper itself

Abstract

The Quality of Life Scale (QLS) is a frequently used semistructured interview for the assessment of functional outcomes in schizophrenia. Despite the use of the QLS for over 30years, the original 4-factor structure of the instrument (Interpersonal Relations, Instrumental Role, Intrapsychic Foundations, and Common Objects and Activities) has not been rigorously examined. Exploratory factor analyses (EFAs) and confirmatory factor analyses (CFAs) were used to evaluate the factor structure of the QLS in two independent datasets, including a mixed diagnostic sample of multi-episode participants (N=247), and a sample of individuals with a first episode of psychosis (N=337). A CFA with the first dataset indicated a poor fit for the 4-factor model of the QLS. Subsequent EFAs on this dataset led to a more promising 3-factor solution including 16/21 of the QLS items, which were similar to the first 3 of 4 factors originally proposed for the QLS. CFAs on the same dataset indicated that the 3-factor model for the QLS-Revised (QLS-R) fit the data well. This factor structure was evaluated with the second dataset using CFA and was also found to be fit the data well. The results support the robustness of the 3-factor model of the QLS-R in schizophrenia and mixed diagnostic samples. Future research should evaluate the validity of the 3-factor model of the QLS-R, and consider the merits of changing the name of the Intrapsychic Foundations factor to Motivation.

Indexed as

Interview, PsychologicalQuality of LifeSchizophrenic PsychologyFactor Analysis, StatisticalFemaleFollow-Up StudiesHumansMaleMiddle AgedPilot ProjectsSchizophreniaYoung AdultConfirmatory factor analysisExploratory factor analysisPsychosocial functioningQuality of life scaleRecoveryStructural equation modeling

Identifiers

PMID27756514
PMCPMC5365361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.