Evidence map›Paper›PMID 27756450›Full record

SynthesisJournal of the International AIDS Society2016

Barriers and facilitators of interventions for improving antiretroviral therapy adherence: a systematic review of global qualitative evidence.

Qingyan Ma, Lai Sze Tso, Zachary C Rich, Brian J Hall, Rachel Beanland, Haochu Li, Mellanye Lackey, Fengyu Hu, Weiping Cai, Meg Doherty and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the International AIDS Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  8. Concerns of Parental HIV Disclosure in China.Clinical nursing research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qingyan MaUniversity of North Carolina Project-China, Guangzhou, China.
Lai Sze TsoUniversity of North Carolina Project-China, Guangzhou, China.
Zachary C RichUniversity of North Carolina Project-China, Guangzhou, China.
Brian J HallDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Rachel BeanlandDepartment of HIV/AIDS, World Health Organization, Geneva, Switzerland.
Haochu LiUniversity of North Carolina Project-China, Guangzhou, China.
Mellanye LackeySpencer S. Eccles Health Sciences Library, University of Utah, Salt Lake City, UT, USA.
Fengyu HuGuangzhou Eighth People's Hospital, Guangzhou, China.
Weiping CaiGuangzhou Eighth People's Hospital, Guangzhou, China.
Meg DohertyDepartment of HIV/AIDS, World Health Organization, Geneva, Switzerland.
Joseph D TuckerUniversity of North Carolina Project-China, Guangzhou, China.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Spurring Innovation in HIV Testing and Linkage: A Crowdsourcing Approach -Diversity SupplementR01AI114310 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TUCKER, JOSEPH DAVID, WEI, CHONGYI · 2014 to 2018
$3.3M
UNC-South China STD Research Training CenterD43TW009532 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COHEN, MYRON SCOTT, TUCKER, JOSEPH DAVID · 2013 to 2017
$1.3M
FIC NIH HHS D43 TW009532NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI114310World Health Organization 001
6 · The paper itself

Abstract

introductionQualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking.

methodsWe searched 19 databases to identify studies presenting primary qualitative data on the experiences, attitudes and acceptability of interventions to improve ART adherence among PLHIV and treatment providers. We used thematic synthesis to synthesize qualitative evidence and the CERQual (Confidence in the Evidence from Reviews of Qualitative Research) approach to assess the confidence of review findings.

resultsOf 2982 references identified, a total of 31 studies from 17 countries were included. Twelve studies were conducted in high-income countries, 13 in middle-income countries and six in low-income countries. Study populations focused on adults living with HIV (21 studies,

conclusionsOur study evaluated adherence interventions based on qualitative data from PLHIV and health providers. The study underlines the importance of incorporating social and cultural factors into the design and implementation of interventions. Further qualitative research is needed to evaluate ART adherence interventions.

Indexed as

Medication AdherenceHIV InfectionsHumansART adherencehealth policyinterventionqualitative researchsystematic review

Identifiers

PMID27756450
PMCPMC5069281

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.