ArticleMalaria journal2016
Assessing temporal associations between environmental factors and malaria morbidity at varying transmission settings in Uganda.
Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spatial and spatio-temporal methods for mapping malaria risk: a systematic review.BMJ global health · 2020Pooled it
- A national spatial prioritisation framework for the targeted expansion of essential sickle cell disease services across health-facility catchments in Uganda.BMC global and public health · 2026Article
- Hotspot Mapping, Spatiotemporal Clustering and Forecasting of Malaria Incidence in Uganda, 2014-2023: Strategies to Inform Targeted Public Health Interventions.Journal of epidemiology and global health · 2026Article
- Identification of malaria hotspots in southwestern Benin through spatial joint modelling of malaria incidence and vector abundance.Malaria journal · 2026Article
- Climate-driven malaria mortality among children in malaria-endemic areas of Uganda.BMC public health · 2025Article
- Modelling the impact of climatic and environmental variables on malaria incidence in Tanzania: Implications for achieving the WHO's 2030 Targets.PLOS global public health · 2025Article
- Vegetation index and livestock practices as predictors of malaria transmission in Nigeria.Scientific reports · 2024Article
- Exploring malaria prediction models in Togo: a time series forecasting by health district and target group.BMJ open · 2024Article
- Climatic, land-use and socio-economic factors can predict malaria dynamics at fine spatial scales relevant to local health actors: Evidence from rural Madagascar.PLOS global public health · 2023Article
- Associations between environmental covariates and temporal changes in malaria incidence in high transmission settings of Uganda: a distributed lag nonlinear analysis.BMC public health · 2021Article
- International lineages of Salmonella enterica serovars isolated from chicken farms, Wakiso District, Uganda.PloS one · 2020Article
- Malaria Burden through Routine Reporting: Relationship between Incidence and Test Positivity Rates.The American journal of tropical medicine and hygiene · 2019Article
- The catastrophic and impoverishing effects of out-of-pocket healthcare payments in Kenya, 2018.BMJ global health · 2019Article
- Describing interaction effect between lagged rainfalls on malaria: an epidemiological study in south-west China.Malaria journal · 2017Article
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6 authors.
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Abstract
backgroundEnvironmental factors play a major role in transmission of malaria given their relationship to both the development and survival of the mosquito and parasite. The associations between environmental factors and malaria can be used to inform the development of early warning systems for increases in malaria burden. The objective of this study was to assess temporal relationships between rainfall, temperature and vegetation with malaria morbidity across three different transmission settings in Uganda.
methodsTemporal relationships between environmental factors (weekly total rainfall, mean day time temperature and enhanced vegetation index series) and malaria morbidity (weekly malaria case count data and test positivity rate series) over the period January 2010-May 2013 in three sites located in varying malaria transmission settings in Uganda was explored using cross-correlation with pre-whitening. Sites included Kamwezi (low transmission), Kasambya (moderate transmission) and Nagongera (high transmission).
resultsNagongera received the most rain (30.6 mm) and experienced, on average, the highest daytime temperatures (29.8 °C) per week. In the study period, weekly TPR and number of malaria cases were highest at Kasambya and lowest at Kamwezi. The largest cross-correlation coefficients between environmental factors and malaria morbidity for each site was 0.27 for Kamwezi (rainfall and cases), 0.21 for Kasambya (vegetation and TPR), and -0.27 for Nagongera (daytime temperature and TPR). Temporal associations between environmental factors (rainfall, temperature and vegetation) with malaria morbidity (number of malaria cases and TPR) varied by transmission setting. Longer time lags were observed at Kamwezi and Kasambya compared to Nagongera in the relationship between rainfall and number of malaria cases. Comparable time lags were observed at Kasambya and Nagongera in the relationship between temperature and malaria morbidity. Temporal analysis of vegetation with malaria morbidity revealed longer lags at Kasambya compared to those observed at the other two sites.
conclusionsThis study showed that temporal associations between environmental factors with malaria morbidity vary by transmission setting in Uganda. This suggests the need to incorporate local transmission differences when developing malaria early warning systems that have environmental predictors in Uganda. This will result in development of more accurate early warning systems, which are a prerequisite for effective malaria control in such a setting.
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