Evidence map›Paper›PMID 27756222›Full record

ArticleBMC microbiology2016

Analysis and description of the stages of Aspergillus fumigatus biofilm formation using scanning electron microscopy.

Alejandra Itzel González-Ramírez, Adrián Ramírez-Granillo, María Gabriela Medina-Canales, Aída Verónica Rodríguez-Tovar, María Angeles Martínez-Rivera

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. The Janus Face ofVeterinary sciences · 2026
    Review
  3. Article
  4. Biofilm Formation inMicroorganisms · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Fungal Biofilm: An Overview of the Latest Nano-Strategies.Antibiotics (Basel, Switzerland) · 2025
    Review
  10. Fungal biofilms in human health and disease.Nature reviews. Microbiology · 2025
    Review
  11. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  12. Article
  13. TheFrontiers in cellular and infection microbiology · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Biofilm Formation by Chromoblastomycosis FungiJournal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alejandra Itzel González-RamírezLaboratorio de Micología Médica, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas (ENCB), Instituto Politécnico Nacional (IPN), Carpio y Plan de Ayala s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, 11340, Mexico City, Mexico.
Adrián Ramírez-GranilloUnidad de Microscopía ENCB, Instituto Politécnico Nacional (IPN), 11340, Mexico City, Mexico.
María Gabriela Medina-CanalesLaboratorio de Micología Médica, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas (ENCB), Instituto Politécnico Nacional (IPN), Carpio y Plan de Ayala s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, 11340, Mexico City, Mexico.
Aída Verónica Rodríguez-TovarLaboratorio de Micología Médica, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas (ENCB), Instituto Politécnico Nacional (IPN), Carpio y Plan de Ayala s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, 11340, Mexico City, Mexico. avrodriguez@hotmail.com.
María Angeles Martínez-RiveraLaboratorio de Micología Médica, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas (ENCB), Instituto Politécnico Nacional (IPN), Carpio y Plan de Ayala s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, 11340, Mexico City, Mexico. angeles.12mar@hotmail.com.
Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiofilms are a highly structured consortia of microorganisms that adhere to a substrate and are encased within an extracellular matrix (ECM) that is produced by the organisms themselves. Aspergillus fumigatus is a biotechnological fungus that has a medical and phytopathogenic significance, and its biofilm occurs in both natural and artificial environments; therefore, studies on the stages observed in biofilm formation are of great significance due to the limited knowledge that exists on this specific topic and because there are multiple applications that are being carried out.

resultsGrowth curves were obtained from the soil and clinical isolates of the A. fumigatus biofilm formation. The optimal conditions for both of the isolates were inocula of 1 × 10

conclusionsTo our knowledge, this is the first time that, in vitro, scanning electronic microscopy (SEM) images of the stages of A. fumigatus biofilm formation have been presented with a particular emphasis on the high hyphal organization and in diverse ECM to observe biofilm maturation.

Indexed as

AspergillosisAspergillus fumigatusBiofilmsCulture MediaExtracellular MatrixFungal ProteinsGerminationHumansHyphaeMexicoMicroscopy, Electron, ScanningSoil MicrobiologySpores, FungalTemperatureCulture MediaFungal ProteinsAspergillus fumigatus biofilmMicrohyphaeScanning electronic microscopy (SEM)Stages of biofilm

Identifiers

PMID27756222
PMCPMC5069814
OpenAlexW2534486500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.