Evidence map›Paper›PMID 27756174›Full record

ArticleDisability and rehabilitation2018

Association of self-reported cognitive concerns with mobility in people with lower limb loss.

Valerie E Kelly, Sara J Morgan, Dagmar Amtmann, Rana Salem, Brian J Hafner

Open access · greenAbstract read
In one paragraph

Article in Disability and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Valerie E Kellya Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
Sara J Morgana Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
Dagmar Amtmanna Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
Rana Salema Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
Brian J Hafnera Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
University of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Julie Mathieu · 1986 to 2026
$41.4M
A Client-Based Outcome System for Individuals with Lower Limb AmputationR01HD065340 · NICHD · UNIVERSITY OF WASHINGTON · PI HAFNER, BRIAN J · 2014 to 2022
$2.7M
A Client-Based Outcome System for Individuals with Lower Limb AmputationU01HD065340 · NICHD · UNIVERSITY OF WASHINGTON · PI HAFNER, BRIAN J · 2010 to 2013
$2.0M
NICHD NIH HHS R01 HD065340NICHD NIH HHS U01 HD065340NIDDK NIH HHS P30 DK017047
6 · The paper itself

Abstract

purposeThis study tested the hypothesis that greater perceived cognitive concerns are associated with worse mobility in a cohort of prosthesis users with lower limb loss (LLL).

methodWe performed a secondary analysis of cross-sectional self-report data from a volunteer sample of people with LLL due to dysvascular and non-dysvacular causes. Perceived cognitive difficulties were assessed using the Quality of Life in Neurological Disorders Applied Cognition - General Concerns (Neuro-QoL ACGC). Mobility was measured with the Activities-Specific Balance Confidence Scale (ABC) and the Prosthetic Limb Users Survey of Mobility (PLUS-M). Simple linear regressions examined univariate relationships between cognitive concerns and mobility. Multiple linear regression analyses included demographic and amputation-related variables that could influence this relationship.

resultsAnalysis of data from 1291 people with LLL demonstrated that greater cognitive concerns, measured by the Neuro-QoL ACGC, were associated with poorer perceived mobility, measured by both ABC and PLUS-M instruments. This relationship remained statistically significant after adjusting for demographic and amputation-related factors.

conclusionsThese results suggest that greater cognitive concerns are associated with worse mobility among a broad range of people with LLL. An improved understanding of this relationship is critical for optimizing rehabilitation outcomes for this population. Implications for rehabilitation Rehabilitation for people with lower limb loss (LLL) typically focuses on physical impairments and mobility limitations, but cognition is increasingly recognized to have an impact on functional outcomes. Greater perceived cognitive concerns are associated with poorer mobility among a broad range of people with LLL, even when adjusting for demographic and amputation-related factors. Cognitive status can impact relevant rehabilitative outcomes, including mobility, and should be considered when planning prosthetic and therapeutic interventions.

Indexed as

AmputeesCognition DisordersMental CompetencyQuality of LifeAgedAmputation, SurgicalCohort StudiesCross-Sectional StudiesFemaleHumansLower ExtremityMaleMiddle AgedMobility LimitationSelf ReportTreatment OutcomeamputationArtificial limbscognition disordersmobility limitationregression analysisrehabilitationself report

Identifiers

PMID27756174
PMCPMC5720823
OpenAlexW2538118882

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.