ArticlePloS one2016
Characterization of Triticum aestivum Abscisic Acid Receptors and a Possible Role for These in Mediating Fusairum Head Blight Susceptibility in Wheat.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Pan-Genome-Based Characterization of the PYL Transcription Factor Family inPlants (Basel, Switzerland) · 2025Article
- Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii.Molecular biotechnology · 2025Article
- Abscisic Acid Can Play a Dual Role in thePlants (Basel, Switzerland) · 2025Article
- Genome-Wide Analysis of the PYL Gene Family inInternational journal of molecular sciences · 2024Article
- Article
- Fusarium Head Blight Infection Induced Responses of Six Winter Wheat Varieties in Ascorbate-Glutathione Pathway, Photosynthetic Efficiency and Stress Hormones.Plants (Basel, Switzerland) · 2023Article
- Article
- Virus-Induced Gene Silencing (VIGS): A Powerful Tool for Crop Improvement and Its Advancement towards Epigenetics.International journal of molecular sciences · 2023Review
- Potential Targets for CRISPR/Cas Knockdowns to Enhance Genetic Resistance Against Some Diseases in Wheat (Frontiers in genetics · 2022Review
- Article
- Genome-wide identification of ABA receptor PYL/RCAR gene family and their response to cold stress inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- UAV-Based Thermal, RGB Imaging and Gene Expression Analysis Allowed Detection of Fusarium Head Blight and Gave New Insights Into the Physiological Responses to the Disease in Durum Wheat.Frontiers in plant science · 2021Article
- A cosmopolitan fungal pathogen of dicots adopts an endophytic lifestyle on cereal crops and protects them from major fungal diseases.The ISME journal · 2020Article
- Genome-wide identification and characterization of ABA receptor PYL gene family in rice.BMC genomics · 2020Article
- Abscisic Acid-Enemy or Savior in the Response of Cereals to Abiotic and Biotic Stresses?International journal of molecular sciences · 2020Review
- Germplasms, genetics and genomics for better control of disastrous wheat Fusarium head blight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- The modulation of stomatal conductance and photosynthetic parameters is involved in Fusarium head blight resistance in wheat.PloS one · 2020Article
- Searching for FHB Resistances in Bread Wheat: Susceptibility at the Crossroad.Frontiers in plant science · 2020Review
- Genome-wide identification and characterization of ABA receptor PYL/RCAR gene family reveals evolution and roles in drought stress in Nicotiana tabacum.BMC genomics · 2019Article
- Abscisic Acid Receptors and Coreceptors Modulate Plant Water Use Efficiency and Water Productivity.Plant physiology · 2019Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abscisic acid (ABA) is a well-characterized plant hormone, known to mediate developmental aspects as well as both abiotic and biotic stress responses. Notably, the exogenous application of ABA has recently been shown to increase susceptibility to the fungal pathogen Fusarium graminearum, the causative agent of Fusarium head blight (FHB) in wheat and other cereals. However roles and mechanisms associated with ABA's modulation of pathogen responses remain enigmatic. Here the identification of putative ABA receptors from available genomic databases for Triticum aestivum (bread wheat) and Brachypodium distachyon (a model cereal) are reported. A number of these were cloned for recombinant expression and their functionality as ABA receptors confirmed by in vitro assays against protein phosphatases Type 2Cs. Ligand selectivity profiling of one of the wheat receptors (Ta_PYL2DS_FL) highlighted unique activities compared to Arabidopsis AtPYL5. Mutagenic analysis showed Ta_PYL2DS_FL amino acid D180 as being a critical contributor to this selectivity. Subsequently, a virus induced gene silencing (VIGS) approach was used to knockdown wheat Ta_PYL4AS_A (and similar) in planta, yielding plants with increased early stage resistance to FHB progression and decreased mycotoxin accumulation. Together these results confirm the existence of a family of ABA receptors in wheat and Brachypodium and present insight into factors modulating receptor function at the molecular level. That knockdown of Ta_PYL4AS_A (and similar) leads to early stage FHB resistance highlights novel targets for investigation in the future development of disease resistant crops.
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