ArticleThe Pediatric infectious disease journal2017
Burden of Severe Respiratory Syncytial Virus Disease Among 33-35 Weeks' Gestational Age Infants Born During Multiple Respiratory Syncytial Virus Seasons.
Article in The Pediatric infectious disease journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Respiratory infections in children born preterm in low and middle-income countries: A systematic review.Pediatric pulmonology · 2022Pooled it
- Burden of respiratory syncytial virus hospitalisation among infants born at 32-35 weeks' gestational age in the Northern Hemisphere: pooled analysis of seven studies.Epidemiology and infection · 2020Pooled it
- Lung ultrasound for the diagnosis of pneumonia in children with acute bronchiolitis.BMC pulmonary medicine · 2018Trial
- Cost-effectiveness of rule-based immunoprophylaxis against respiratory syncytial virus infections in preterm infants.European journal of pediatrics · 2018Trial
- Article
- Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Adherence to Palivizumab for Respiratory Syncytial Virus Prophylaxis in Romanian Infants.Vaccines · 2025Article
- Respiratory syncytial virus subtypes in children with bronchiolitis: does it correlate with clinical severity?BMC infectious diseases · 2024Article
- Are Babies Born Preterm High-Risk Asthma Candidates?Journal of clinical medicine · 2023Review
- Winds of change a tale of: asthma and microbiome.Frontiers in microbiology · 2023Review
- Human Respiratory Syncytial Virus Infections among Hospitalized Children in Poland during 2010-2020: Study Based on the National Hospital Registry.Journal of clinical medicine · 2022Article
- Human respiratory syncytial virus diversity and epidemiology among patients hospitalized with severe respiratory illness in South Africa, 2012-2015.Influenza and other respiratory viruses · 2022Article
- Lung ultrasound to predict pediatric intensive care admission in infants with bronchiolitis (LUSBRO study).European journal of pediatrics · 2021Observational
- Etiology, clinical characteristics and coinfection status of bronchiolitis in Suzhou.BMC infectious diseases · 2021Article
- [Epidemiological characteristics of respiratory syncytial virus in hospitalized children with acute lower respiratory tract infection in Chongqing, China, from 2013 to 2018: an analysis of 2 066 cases].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Respiratory syncytial virus hospitalizations in US preterm infants after the 2014 change in immunoprophylaxis guidance by the American Academy of Pediatrics.Journal of perinatology : official journal of the California Perinatal Association · 2020Review
- Lung Ultrasound and Clinical Progression of Acute Bronchiolitis: A Prospective Observational Single-Center Study.Medicina (Kaunas, Lithuania) · 2020Observational
- Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy.Italian journal of pediatrics · 2019Article
- Risk scoring tool to predict respiratory syncytial virus hospitalisation in premature infants.Pediatric pulmonology · 2018Article
- Interaction between healthcare professionals and parents is a key determinant of parental distress during childhood hospitalisation for respiratory syncytial virus infection (European RSV Outcomes Study [EROS]).Acta paediatrica (Oslo, Norway : 1992) · 2018Observational
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundModerate-late preterm infants, 33-35 weeks' gestational age (wGA), are at increased risk for respiratory syncytial virus hospitalization (RSVH). The objective of this study is to quantify the burden of RSVH in moderate-late preterm infants.
methodsA pooled analysis was conducted on RSVH from 7 prospective, observational studies in the Northern Hemisphere from 2000 to 2014. Infants' 33-35 wGA without comorbidity born during the respiratory syncytial virus season who did not receive respiratory syncytial virus immunoprophylaxis were enrolled. Data for the first confirmed RSVH during the season (+1 month) were analyzed. Incidence and hospitalization rate per 100 patient-seasons, intensive care unit admission and length of stay (LOS), oxygen support, mechanical ventilation and overall hospital LOS were assessed.
resultsThe pooled analysis comprised 7,820 infants; 267 experienced a confirmed RSVH at a median age of 8.4 weeks. The crude pooled RSVH incidence rate was 3.41% and the rate per 100 patient-seasons was 4.52. Median hospital LOS was 5.7 days. A total of 22.2% of infants required intensive care unit admission for a median LOS of 8.3 days. A total of 70.4% received supplemental oxygen support for a median of 4.9 days, and 12.7% required mechanical ventilation for a median of 4.8 days.
conclusionsThe burden of RSVH in moderate-late, 33-35 weeks' wGA preterm infants without comorbidities born during the viral season in Northern Hemisphere countries is substantial. Severe cases required prolonged and invasive supportive therapy.
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